Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12712 Pd-0325901 GSE70138 HME1 Human 24h 3.33uM EID0038
Types Number Response transcription factors
Up-regulation 183 MEF2C; NFIL3; TSC22D3; NFKBIA; HDAC5; TRIM16; NFKB2; FOXO4; WNT4; ARNT; EPAS1; SMARCD2; OSR2; SETDB1; TCEA2; CEBPD; FOXO3; CSDC2; NFE2L2; PNRC1; HBP1; DBP; ZNF768; HES1; MZF1; CERS4; TLE1; IRF6; TOX; MED12; CALCOCO1; RARB; SREBF1; TFAP2A; PCBD1; PBXIP1; PRDM2; JUND; PBX1; MKL1; TP63; ARID4B; RFX2; PDLIM1; REL; ING4; ZNF444; CTBP1; ADRB2; MEIS1; TAF11; ZNF415; FOXO1; HCFC2; ZNF652; PEG3; KLF5; ZHX2; HDAC9; JUP; ELF3; CREG1; ZNF576; FOXI1; RBFOX2; ZSCAN31; MED24; TRIM29; BACH2; KDM5B; IRF1; RING1; SOX11; TCF4; PCGF2; CBX7; ARID5B; NFIC; SMARCD3; EN1; TCF7L1; PPP1R13L; RNF10; VPS72; CDIP1; BCL3; AIP; TFEB; SIAH2; DDX17; MAF; ZMIZ1; ATF3; COPS2; BCL11A; SSBP3; TEAD3; ZNF426; NHLH2; DPF2; PITX1; ETS2; TP53; FLI1; ZNF133; ELF4; KLF3; BCL6; PAX6; TRPS1; ZNF264; ZNF224; TRIM22; TWIST1; NCOA2; ZNF688; MEOX2; SRCAP; IRF9; STAT2; MEF2A; SIX3; TRAK1; PHF20; ZNF33B; NFE2L1; SUPT4H1; HOXA5; ZKSCAN1; ZNF331; PCGF3; CBFA2T3; TCEB2; PAWR; INSR; ERG; CERS6; L3MBTL1; MEIS2; ELF1; ZNF532; RXRA; AES; CUX1; LITAF; HLF; MKL2; TLE2; SSBP2; MAFB; FOXN3; KLF11; HMGN3; MTA1; NR1H2; ZFPM2; VGLL4; ZNF83; HHEX; EMX2; NR1H3; FOSL2; DLX5; DACH1; AHR; SHOX2; RBPMS; ZNF91; KLF4; BTG1; GATA6; ID3; ELF5; TOX3; ZIC1; CUX2; PIR; TXNIP; PLAGL1; MECOM; ZNF423; ARNT2; RELB
Down-regulation 92 HMGA2; BRCA1; HMG20B; CCNA2; ETV1; FOSL1; DNMT1; MYC; THAP11; SUZ12; MYCBP; XBP1; EGR1; CENPF; PA2G4; RAN; TFDP1; NPM1; EZH2; BHLHE40; PPRC1; PPARG; DNAJC2; TRIB3; NPAT; ETV5; WHSC1; HMGA1; PSMC3IP; C1QBP; RUVBL1; MED17; ZNF562; CBX3; YWHAB; AGO2; POU4F1; ETV4; PURA; BLM; JARID2; E2F3; EGR3; ENO1; PHIP; EGR4; TAF1A; SSRP1; CBFB; GCFC2; SATB2; TFAM; BCLAF1; RNF138; RNF4; HMGB2; SFPQ; PMS1; FOXM1; BTAF1; CDK2; SOX10; MYBL1; URI1; GTF3A; HMGB1; SMAD2; MTF2; CBX5; KLF2; WWTR1; MYB; ING3; EGR2; BCL11B; BAZ1A; ABL1; ZBTB18; HOXB7; CTBP2; SUV39H1; HLTF; ZNF217; NANOG; TCERG1; SMAD3; KDM5D; NR2F2; OLIG2; NKX2-2; LOXL2; BHLHE41