Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12614 Cgp-60474 GSE70138 HME1 Human 24h 0.04uM EID0038
Types Number Response transcription factors
Up-regulation 532 EGR1; E2F2; RFX1; THRB; PROP1; GBX1; MEF2C; ZNF710; MED12; TTF2; NR4A3; ACTL6B; ZNF154; WNT4; ZFHX2; ESR1; ZNF75D; ZSCAN2; SSX7; PRDM12; HNF4A; PAX3; HLX; PDX1; VPS72; NEUROG1; HIPK2; MYBL2; CDX4; KMT2D; TAF6L; HIF3A; HAND2; TBX10; VENTX; LBX1; MAFK; THRA; NKX6-1; TULP1; MAML3; ESRRB; ZNF816; SOX17; RFX2; RFX3; TFDP3; HEYL; ZNF671; HOXB1; HESX1; PAX1; RBPJL; CBX2; TEF; HNF1A; PAX6; PRDM16; ZNF331; NR1I3; GFI1B; NEUROD4; ZFPM2; FOXB1; SOX2; NFIX; SOX14; IKZF4; ZNF768; CIITA; FOXH1; MAK; ZNF215; HAND1; HOXC5; ZBTB7B; SOX1; ALX4; GBX2; NR6A1; ALX3; NEUROG3; POU6F2; VGLL1; DOT1L; ZNF350; STAT5B; FOXE3; ARID3B; TSHZ2; MBD4; NFATC4; TBX19; NEUROG2; MAPK8IP1; HOXC8; ONECUT1; TAF1C; CHD2; ZIM2; SOX3; PRDM14; ZNF467; TUB; GSC2; ATF6B; AIRE; EMX1; ONECUT2; PCBD1; CEBPE; FOS; NR5A2; ZNF221; ZNF551; NKX2-5; PRDM9; ZIC3; RAX; ERBB4; POU3F3; FEZF2; POU4F3; HOXA6; WHSC1L1; HSF4; CRX; HOXB5; NEUROD2; FOXD3; EYA3; CDIP1; MXD3; HOXD12; SIX6; NR4A1; HNF1B; RSF1; AFF3; ASCL3; MLLT1; ZNF550; POU3F4; FOXD2; ZNF493; RARG; ETV2; PITX3; SCRT1; PRMT2; HOXB13; PAX8; ZNF358; HINFP; TCEA2; EHMT2; ZNF586; ZNF343; NKX2-8; ZNF507; SCAI; ZNF264; DLX6; TBX6; HOXA3; ATF7; ZNF552; AFF2; PSMC3; E2F4; ETV3; ZNF197; NR5A1; SPI1; CALCOCO1; SALL2; NPAS1; PGR; CSDE1; ZIC4; ATN1; NHLH2; WDR77; BCL11A; ZNF771; ZNF682; SRY; LHX3; ARID3A; GRHL2; MEIS2; BRWD1; HOXB8; HDAC5; HIC1; TLX2; SIX5; RING1; MXI1; CIR1; AR; NR2E1; ING4; ZNF74; ZNF835; ZNF695; DBP; PAX7; DLX5; WT1; IKZF3; TONSL; ZNF549; ZNF814; TBR1; TCF21; NUP62; TAF1; NR0B2; RORB; ATF3; NRL; SHOX; LHX6; MZF1; ZNF667; ATOH1; TLX1; ZXDC; ZNF93; CSDC2; TBX5; OVOL1; PHOX2A; IRF6; IRF1; POU6F1; ZFP2; PRDM8; TEAD3; SOX21; IRF8; PAX4; ZNF219; DCC; MLLT10; ZKSCAN3; HOXD9; TBX4; TRPS1; ZNF80; ZKSCAN8; ZSCAN16; DLX4; KLF8; MED25; L3MBTL1; ZNF407; FOXP3; PRDM5; ZNF696; EMX2; FLI1; ZNF780B; CREBL2; YEATS2; TAF6; BARX1; SOX5; GLI2; ZNF345; ZNF471; RORC; ZNF749; E2F5; CARF; INSM1; EBF2; ASCL2; LZTR1; THAP9; ZNF665; AEBP1; ZNF652; ZNF362; BARX2; VHL; HNF4G; ZBTB7C; ZNF778; TWIST1; TP73; ZNF444; ZNF235; GRIP1; GCM2; ZNF787; BNC2; FOXJ1; ZNF440; ZNF107; NFE2L3; POU1F1; ZBTB48; CAMTA1; ZNF157; NHLH1; FOXC2; OVOL2; KAT2B; NR4A2; ZNF701; ESR2; CBX8; ZNF613; NOC2L; HOXD13; MSX2; DAXX; PHOX2B; ZKSCAN4; ZNF674; SPDEF; SP4; ZNF391; FOSB; LMO1; SCMH1; ZNF334; STAT2; PAWR; HOXA2; MECP2; SOX18; NAB2; CD3D; GLI1; ESRRG; TAL1; ZNF536; ZNF81; GCM1; ZNF711; TFDP2; HOXA4; MEIS1; JAK2; CBFA2T3; PRRX1; ZNF423; ZNF223; ZNF117; CBX7; RXRG; CREM; CERS6; LIN28A; CNBP; IRF5; SUPT3H; SRCAP; ZNF33B; ZNF141; TBX21; PRDM13; MYRF; HBP1; PRDM2; PEG3; ZSCAN9; ZNF177; NKX3-2; TAF9B; CNOT3; FOXL2; NEUROD6; IRF3; EVX1; GATA3; ZNF10; TLX3; EGR3; ZNF205; PRDM1; MYT1; ETV7; ZNF611; RBFOX2; POU3F2; ENY2; SUMO1; TFDP1; SKIL; HOXD3; BPTF; EGR2; ZNF254; CERS4; ARRB1; KLF15; CAMTA2; ARID5A; POU4F2; HIC2; TFAP2A; BRD7; MYF6; ID4; KAT2A; ZNF688; ZNF304; PBX2; EZH1; SUPT5H; STAT5A; KDM5C; TGIF2; GATA6; CREG1; TFEC; GATA1; ZNF587; ZNF135; EGR4; CALR; ZNF43; HOXB2; ELF4; ZNF85; E2F3; CUX2; ACTL6A; SMARCA1; MYCN; NFE2; ZNF224; TOX; HMBOX1; SIX3; CDX1; HOXD11; ZNF124; NKX2-1; PCGF3; TBX1; HHEX; FOXA2; TCF15; HEY1; SLC2A4RG; CBX4; ID3; NR1H3; ZNF133; HMGXB3; ZBED2; PBX3; HOXB6; PEX2; CDX2; REL; MECOM; E2F8; ZIC1; ZEB1; TDP2; ZSCAN31; ST18; TCF7; NFAT5; IRF9; TRIM24; ZNF532; HEY2; HDAC9; MYCL; SHOX2; FOXF1; INSR; FOXF2; ZNF544; NEUROD1; ELF5; ZNF175; TULP3; CREB3L2; ZNF83; ZSCAN18; NCOA2; CUX1; NR1H2; LYL1; NR2F1; SPIB; CRYM; TCF7L1; EHF; MXD4; PLAGL1; POU5F1B; SOX11; ARNT2; ZNF195; ZNF165; KLF11; MTA1; MSX1; ZFHX4; MEOX2; DACH1; ID1; ZNF512B; IRF7; LEF1; OSR2; MYBL1; ZNF589; MNDA; ZBTB20; MAF; LMCD1; NKX2-2; TBX2; TGFB1; NANOG; GATA2; PSIP1; HOXB7; ASCL1; BHLHE41; NFATC3; CREB1
Down-regulation 210 MYC; TSC22D3; CRK; CCNA2; TBP; NFKBIA; FHL2; CEBPB; RBM14; SNW1; XBP1; HNRNPD; EED; AATF; NFIL3; CDK7; SFPQ; ADNP; FOSL1; NCOA6; HDAC2; SOX4; KAT6A; POLR2A; ADRB2; ABL1; SCAND1; YBX3; SNAI2; KAT7; REST; SNIP1; HSF2; DPF2; HOXA5; NRBF2; MED6; TAF5; SP3; TRIM32; HES1; FOXO3; PHF20; BHLHE40; TAF1D; EZH2; TSC22D2; RBBP4; PURA; SMARCA5; CTR9; MED17; TLE1; MBD2; ING2; BRCA1; UBE2I; BRD3; TBPL1; THAP1; JARID2; TRIM29; BMI1; BRD8; BRPF1; TULP4; KAT5; SUZ12; ZNF263; ITGB3BP; VEZF1; SAP30; ELF1; MED4; MED23; SAFB2; USP22; CCDC59; ZBTB11; CBFB; BLM; KLF2; ECD; CHD1; NPM1; RARA; PCGF2; CRY1; ZFP36L2; RELA; HOXC6; MED20; RLF; ATF1; DNAJC2; PUF60; MLXIP; ZFP64; HMGB2; RAN; ADNP2; ZBTB24; BCLAF1; MAGED1; DDIT3; PPRC1; CTBP2; PPARGC1A; SAFB; NELFB; BASP1; RBM39; DR1; ZMYM2; TFAM; YWHAB; NKX3-1; ELK1; JUND; CENPF; RNF111; NPAS2; TRIM28; MLX; GABPB1; ARNTL; BTG1; TRIM16; ZBTB7A; NFYC; NCOA4; NFKB1; NR3C1; ZNF146; MED1; MAX; NR2F2; SMARCE1; ZNF189; TBL1X; CTCF; MTDH; FOXJ3; SMAD1; BCL10; KDM2A; PTTG1; ELK3; NAB1; PLAGL2; AFF1; SMARCA2; ZFP36L1; SUV39H1; TCERG1; IRF2; SATB2; DDX5; SMAD2; CBX5; UBP1; RUNX3; SOX9; RCOR1; RNF4; PSPC1; ERBB2; SF1; APEX1; KDM5D; SIX2; ZBTB18; TP63; TFAP2C; SIX1; ZNF302; HOXA1; CEBPZ; SMAD3; HMGB3; KLF4; ETV5; MYB; TSC22D1; TOB1; HMGB1; NRIP1; MED13; ZNF410; MTF2; ZNF281; TBL1XR1; IRF4; TRIP6; PAX5; RREB1; MEF2A; ZNF217; BAZ1A; TGIF1; BRD4; MAFB; KLF6; FOXD1; RBPMS; RBPJ; FLNA; POU2AF1; HOXC10; NFIB