Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12584 Vorinostat GSE70138 HME1 Human 24h 10uM EID0037
Types Number Response transcription factors
Up-regulation 183 NFIL3; ID2; FOXO4; STAT1; SIN3B; HBP1; ZNF394; CALCOCO1; LDB1; SSBP2; ZNF34; KDM5B; NR4A3; TERF1; ARID5A; RELB; TBPL1; SALL2; LMCD1; HDAC5; JUND; NR4A1; PLAGL1; MXI1; ZNF224; ZBTB40; GATA3; HABP4; JARID2; IRF8; L3MBTL1; PPARD; ZNF160; FOXN3; SND1; TRPS1; HOXC13; CBX7; CSDC2; EZH1; CCNH; GTF2IRD1; DLX4; ZNF91; BCL3; CREG1; REL; POU2F1; ZNF721; RING1; CREM; IRF9; GTF2F1; PBX1; ZBTB17; BANP; NR3C1; ATF3; PBXIP1; TEAD3; ERBB4; NHLH2; TCEB2; INSR; MEOX2; ZNF331; YBX1; SUPT4H1; TFDP2; CERS4; RYBP; MAF; TBX3; NR4A2; MNT; DDIT3; ARNTL; PNRC1; FOS; THRA; TBX21; NAB2; SPEN; NR2C1; ING4; BRD4; RORA; CRK; TCF7; ZNF302; TCEA2; MXD4; HDAC3; TLE2; ZNF611; BTG1; IL16; RUNX3; SAP18; ZNF44; CAMTA1; FOSB; CBFA2T2; HOXB5; SETD3; IRF7; ESR1; EP300; ASCL1; NR0B1; TSG101; ZNF623; FOXF1; MECP2; EYA1; KDM5A; SIX1; ZBTB16; ZNF536; IRF1; HMBOX1; SHOX2; MYCL; HAND1; ZNF117; RLF; STAT4; TULP4; RARA; CREB5; IRF4; ARID5B; ZNF652; MITF; PHF20; ZNF239; DBP; MYT1; HDAC6; BAZ2A; SMARCA1; CERS6; EGR3; CITED2; EHF; MED21; HEY1; FOXA1; NR1H2; TRIM16; HOXB13; SMAD6; WWC1; BBX; EPAS1; KLF11; ZKSCAN1; TOX3; INSM1; PCGF2; PITX1; HOXB2; OSR2; HMG20B; CREB3L2; ELF3; ARNT2; JUP; MEIS1; FOXO1; GATA6; SOX9; DACH1; CD3D; PAX5; MAFB; MYRF; ID3; HDAC9; PEG3; HTATIP2; BHLHE41; CREB1
Down-regulation 101 HMGA2; CCNA2; XBP1; NUP62; FOSL1; FHL2; MYC; FOXM1; DNMT1; ATF1; ZFP64; CHAF1B; CENPF; DEK; WHSC1; BAZ1A; TEAD4; REST; TTF1; PHF2; RBM14; ATF5; GCFC2; HMGB2; CBFB; STAT6; TRIM22; SMARCC1; ZFP36L2; BCLAF1; TFDP1; REXO4; PTTG1; MYBBP1A; MYBL2; NRIP1; ARL2BP; ILF2; WDHD1; PMF1; HNRNPD; CEBPD; BLM; E2F8; TP53; YEATS4; IFI16; ERBB2; YWHAB; YBX3; RBBP8; MAGED1; ZBED4; NFYB; TFCP2; HMGB1; RNF138; ZNF140; SP3; ZNF217; RUNX1; CBX3; POLR2A; BRIP1; PLAGL2; BASP1; BRD3; PTRF; BCL11A; IRF2; SUB1; SUV39H1; MED24; C1QBP; MKL2; ZNF551; TFAP2C; TP63; FLI1; HMGB3; TBL1XR1; CALR; BMI1; AEBP1; TGIF1; ELK3; ZNF512B; POU2AF1; HIPK3; EYA2; MLXIP; STAT5B; ZEB1; FOXC1; KLF5; NFIB; MYBL1; MYB; LEF1; MEF2C; TBX2