Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12554 Bms-509744 GSE70138 HME1 Human 24h 10uM EID0037
Types Number Response transcription factors
Up-regulation 116 TSC22D3; KDM5B; SOX4; FOXO4; MNT; MXI1; CALCOCO1; MEIS1; TFAP2A; NFIL3; SETDB1; INSR; PHF1; PFDN5; EMX2; MED12; ZNF629; KLF11; ING4; CSDC2; SMAD3; KMT2A; ZNF688; NRIP1; PATZ1; HDAC5; YBX1; ZNF354A; JUND; L3MBTL1; ZMIZ1; RORA; AHR; TGIF1; PNRC1; PHOX2B; HBP1; GATA6; ELF4; HMBOX1; TEAD3; NCOA6; HINFP; SIAH2; CEBPD; BCL6; SND1; RSF1; STAT4; ZNF33B; TCEB2; GATA3; ERBB2; CERS4; CREG1; ZNF91; ZNF426; FOXL2; CUX1; BCL3; MTA1; STAT6; ZNF165; CARHSP1; JARID2; FOXN3; FOSB; ZNF768; HEY2; SHOX2; TBL1X; RLF; ZBTB43; TLE1; SOX13; ARID1A; ESR1; PHF20; NCOA2; UBE3A; NR2F2; FOSL2; NR4A2; HIVEP2; NFKBIA; NR4A1; ZNF12; ATF3; ZNF83; TOX; NR1H2; ZFHX3; SMAD2; SCAND1; MITF; TCEA1; MEOX2; BTG1; ELF3; TLE4; ZNF423; ERG; PDLIM1; WT1; CREB5; PBX1; TBX2; ID4; DACH1; TGFB1I1; INSM1; KLF6; MECOM; MYRF; BHLHE41; BASP1
Down-regulation 71 PARP1; CCNA2; MYCBP; EZH2; DNMT1; BRCA1; ZNF274; RUVBL1; GMNN; ITGB3BP; FOXM1; HMGB1; MYBL2; BLM; CENPF; XRCC6; CHAF1B; WHSC1; PTTG1; MAGED1; CDK2; SFPQ; GCFC2; TEAD4; PSMC3IP; E2F8; HEY1; HLTF; WDHD1; PRRX1; RBM14; MLXIP; PITX2; YEATS4; POU2AF1; RBL1; HLF; SLC2A4RG; MLX; DNMT3B; RAN; TAF9B; ACTL6A; HIC2; ILF2; WDR77; HOXA1; CTNNB1; DLX5; MSX1; DMTF1; AEBP1; SUV39H1; TBX3; SOX9; MAFB; ASH2L; HMGB2; SUB1; DLX2; ID1; YWHAB; PAX5; ID3; LEF1; ZSCAN18; SATB2; HHEX; TOX3; MYBL1; MEF2C