Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12543	Osimertinib	GSE70138	HME1	Human	24h	3.33uM	EID0037

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	TSC22D3; TAF1D; GATA2; PMF1; NFIL3; EMX2; TP53; ESR1; SP100; ZNF423; HMBOX1; BTG1; FOXO3; ZNF646; PHOX2B; ZNF14; BRD2; NAB2; CREG1; TCEA2; PATZ1; ZNF430; CHD9; HOXA5; HMG20A; SMARCC2; CIR1; DAXX; YEATS2; ZNF148; IRF9; TERF2; TEAD3; OSR2; HDAC7; BRD4; BCL3; ZNF768; ARID1A; RYBP; CEBPD; ZBTB38; MKL2; MAFB; ZNF205; TRIP6; REL; MEIS1; ZNF12; ZNF266; ETS2; TRIM22; FOXO1; NR1D2; PURA; NFE2L2; SMAD2; NFKBIA; LMCD1; ZNF331; REPIN1; ZBTB16; MXI1; ID3; SMAD1; NFE2L1; TLE1; ELF5; ETV5; POU4F1; SMAD6; KAT6B; TWIST1; NR2F2; NFATC3; MECOM; TAL1; PBX1; TAF10; INSR; TP63; CD3D; PDLIM1; SOX11; LITAF; TGFB1I1; ZNF91; ERG; MEIS2; PEG3; ID1
Down-regulation	78	ETV1; BHLHE40; CCNA2; BNC1; FOXF2; ZBED2; MAX; FOSL1; PIAS4; ARNTL2; FOXM1; CTNNB1; EGR1; SFPQ; NR2E1; NEUROD1; ZIC3; BAZ2B; HIRA; SSX1; ZNF721; HHEX; UBP1; WHSC1; BLM; ST18; SAP30; ATOH1; HIC2; DLX2; PREB; PIAS2; SOHLH2; CITED1; ZBTB20; HIPK1; NLK; PBX3; HOXB13; LIN28A; GATA4; CRY1; MEOX2; TCF7L2; HMG20B; HMGB2; HIPK3; FOXD1; CITED2; FOSB; ENO1; NKX2-2; TBX3; RBPMS; PAX6; BHLHE41; TCF21; PTTG1; FOXG1; FOXA1; HMGN3; ELK3; JAK2; TLE2; FLI1; CEBPG; IRF4; NANOG; PPARG; HOXB6; KLF9; INSM1; HOXD1; KDM5D; ATF3; LEF1; TBX2; MEF2C