Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12514 Gsk-1059615 GSE70138 HME1 Human 24h 1.11uM EID0037
Types Number Response transcription factors
Up-regulation 153 TSC22D3; NFKB2; HOXC4; ZNF266; FOXO4; SND1; HDAC5; GTF2F1; SETDB1; ZNF227; HOXC6; TCEA2; VDR; KDM4C; HDAC4; ZNF688; INSR; APEX1; CALCOCO1; HBP1; SAP18; NCOA2; ZZZ3; EZH1; ZBTB17; NCOA3; SIN3B; SP100; CIR1; CXXC1; REXO4; PIAS4; BRD4; MAX; AATF; EMX2; CBX5; SMAD3; TTF1; HINFP; MED23; CIZ1; DDIT3; NKRF; SIAH2; ELF3; ZNF263; MXI1; MTA1; BTG1; HDAC6; STAT5A; FOXO3; ZNF384; MAFF; TERF2; CBX7; KLF11; AIP; PQBP1; TAF12; UBE2B; PNRC1; TERF1; SOX13; TCF25; TFCP2; ZNF146; CTR9; THRA; ARID1A; ZNF107; EYA2; ZNF23; PBXIP1; NONO; NFIL3; TCEA1; NR1H3; HOXB2; BRD8; ZNF112; HTATIP2; HOXB7; SIRT7; TWIST1; PSPC1; LPIN2; COPS2; ZNF45; FOXL2; FOXN3; KAT8; SMARCB1; ZNF131; CERS4; ZNF3; SPEN; CREB3L1; ZNF573; HMGA1; TRIM22; ELF1; NR4A2; ATF4; WWP1; MEF2A; OSR2; TAF10; HEY2; CREBL2; IRF7; TLE1; ZNF580; SOX17; NFYC; ZMIZ1; FOSL2; BRD2; MED24; COPS5; BACH2; PCGF2; ZNF423; BCL3; KAT6B; TOB1; EHF; HOXC10; PLAG1; RBM39; SHOX2; FOXO1; TFAP2C; ZNF83; CRYM; RORA; ELF5; KAT2B; JUND; STAT5B; IFI16; TGIF1; HDAC9; CEBPD; ESR1; MNDA; TBL1X; HMG20B; CITED2; ATF3; WT1; PEG3
Down-regulation 115 MYCBP; RUVBL1; ZNF274; GTF2A2; SNAI2; CLOCK; BHLHE40; TSC22D2; SMARCD3; PBX3; TFAM; ADRB2; CCNE1; HSBP1; NKX2-1; EWSR1; NR2F6; RAN; WDR77; GABPB1; RUVBL2; MAGED1; ZNF587; MKL2; CTNNB1; WWC1; FOXF1; NKX3-1; FOXG1; DDX5; VEZF1; SMAD7; TRIM29; CDYL; ZNF552; FOSL1; DMTF1; REST; HLTF; PKNOX2; TCF21; TAF9; FOXF2; E2F3; SLC2A4RG; PSIP1; CCNT1; PBRM1; ZNF652; BBX; RXRA; YWHAB; ZBED2; ENO1; ZNF134; MYBL2; DLX2; CBFB; ING2; YBX2; MNX1; ZNF160; SFPQ; ZNF148; SPIB; SMARCA5; TRIM24; TBX3; ILF2; CRY1; PHIP; ZNF512B; ZNF721; ZSCAN18; BRIP1; MYCN; FOXC1; ZNF264; MNAT1; CCNC; NFAT5; RAD21; ZNF551; CTBP2; BMI1; MED13; SOX9; TDP2; HMGB3; HOXA1; PAX6; CALR; PTRF; CREG1; SATB1; MEOX1; KLF4; ELK3; CHD7; POU2AF1; SUB1; ID1; CREB3L2; NR1D2; ID4; MECOM; PPARG; TXNIP; FLNA; TCF4; ASCL1; CREB1; DACH1; HOXA10; MEF2C