Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12490 Ibrutinib GSE70138 HME1 Human 24h 1.11uM EID0037
Types Number Response transcription factors
Up-regulation 114 TSC22D3; ERBB2; TRIM29; PPARG; NFIL3; TRIM22; ZNF665; TP53; PCBD1; MED23; ZNF91; ZFP36L2; ZNF14; SSBP2; ZNF44; TXNIP; FUBP1; ZNF302; ZNF426; ZNF329; SMARCD2; MEOX2; CDIP1; ZNF304; CREG1; IRF6; PLAGL1; ZNF43; PFDN5; HBP1; ZNF606; TCEB2; ZNF268; HOXA5; ZNF415; ARID4A; ZNF134; ZSCAN18; ZNF93; ZKSCAN7; KMT2A; LITAF; ZNF667; TCEA2; MAF; ZSCAN31; ZNF83; ID4; AES; CEBPD; FOXO1; TOB1; ZNF112; ZNF711; MEF2D; FOXN3; SMAD4; ZNF10; ZNF136; ZNF211; L3MBTL1; NFKBIA; ZNF266; ZNF419; ASCL1; ZNF652; ZNF586; SP3; ID3; PNRC1; KAT6B; ZNF468; ZNF331; TLE4; BACH2; KLF13; HMBOX1; NR2C1; ZNF551; TGIF1; ZNF544; MDM2; ID1; MAFB; TBL1XR1; ZBTB1; ZNF430; IRF9; SATB1; TRPS1; NFATC1; BCL11B; ZNF587; EHF; HOXC6; KLF5; STAT4; ZNF423; TCF7L1; NFE2L2; IRF8; OSR2; JUP; IRF1; EDF1; TLE1; NFATC3; BTG1; PEG3; ETS2; SOX11; FLNA; NR2F1; LEF1
Down-regulation 40 HMGA2; ETV1; FOSL1; BHLHE40; DNMT1; TFAP2A; ASH2L; HMGA1; TRIM27; EGR1; CNOT6; ZNF281; PPRC1; BAZ1A; RNF6; ARNTL2; FOSB; TRIB3; ETV4; ZBTB18; POU2AF1; FOXF2; RBPMS; ZMYM2; KAT2B; TRIM32; BATF3; TFAP2C; CBX6; MYBL1; SUV39H1; WT1; HOXB7; SATB2; LOXL2; ATF3; TBX2; BASP1; CREB1; MEF2C