Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12489	Ibrutinib	GSE70138	HME1	Human	24h	3.33uM	EID0037

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	TSC22D3; NR3C1; ZNF219; FOXO3; ZNF688; SSBP2; TRIM29; HEY2; JUP; PFDN5; SMARCD2; BTG1; OSR2; ZHX2; HBP1; PNRC1; CDIP1; SMARCD3; TXNIP; TP53; NR4A3; NFIL3; TCEA2; HOXC4; MAF; IRF6; EMX2; FOXO4; PBXIP1; SSBP3; CREG1; ERBB2; PPP1R13L; ING4; MXI1; HOXC6; TOB1; VDR; KLF11; TERF2; MEIS1; CEBPD; ZFP36L2; GLI1; HDAC7; HR; CIC; HOXA5; NR0B1; REL; RNF141; HDAC4; KMT2A; TRIM16; MED24; RBBP7; CUX1; NAB1; CERS4; ARID5B; STAT4; NFKBIA; PHOX2B; EP300; RARG; HDAC5; BRD8; PHIP; ZNF423; SP140L; ZNF44; TCF7L2; YBX2; SREBF1; HOXD11; ELF3; RXRA; NCOA2; TP63; ZNF117; TFDP2; AR; SAP30; ZMIZ1; ERF; SND1; FOXN3; PATZ1; ZBTB20; TCF7L1; CBFA2T3; IRF1; ZBED1; LITAF; RYBP; CHD9; RBBP8; PHF20; ERBB4; ID4; SMARCA1; TCEA1; GATA3; TLE1; NFE2L2; ZNF580; ZNF430; CREM; EHF; TRIP6; BACH2; IRX5; RORA; MYCN; NFATC3; HMGB2; BHLHE41; TOX; ESR1; VGLL4; ARNT2; TBX2; PDLIM1; INSR; TGIF1; PEG3; HOXB7; ERG; ATF3; GATA6; MAFB; ID3; FOXC1; NR4A2; DACH1
Down-regulation	90	MYCBP; HMGA2; ETV1; BHLHE40; FOSL1; ZNF146; DNMT1; RUVBL1; ARNTL2; CDYL; CCNA2; EGR1; SNAPC4; NCOA3; ZNF557; EGR3; USP16; XBP1; BAZ1A; DDX54; TAF1A; NPAS2; SFPQ; ETV5; DEK; ENY2; UBP1; WHSC1; CTNNB1; MLX; ZNF444; BCL10; AGO2; HMGA1; CTBP1; TRIM27; RNF4; HEY1; ZNF692; IRF7; GATA4; KMT5A; ASH2L; WWP1; PAXBP1; E2F8; TEAD4; HLTF; NKX2-1; IRF8; PPRC1; WDR77; HOXD1; RBM14; ILF2; PSIP1; ZBTB18; CRY1; BMI1; MEOX1; ENO1; CRYM; ZNF587; MYT1L; BNC2; TSC22D1; ELK3; REPIN1; WWC1; ST18; LOXL2; KLF10; ZNF217; FOXG1; KLF6; ZEB1; SUB1; RUNX3; TFAP2C; SUV39H1; FOSB; HHEX; PBX3; MYRF; TCF4; PPARG; MEIS2; ASCL1; CREB1; MEF2C