Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12447	Cgp-60474	GSE70138	HME1	Human	24h	3.33uM	EID0037

Response Information :

Types	Number	Response transcription factors
Up-regulation	298	EGR1; CIITA; E2F2; SOX2; PCBD1; PDX1; HOXB1; ZNF117; NR0B2; TCEA2; THRB; KAT2B; KAT2A; FOS; VENTX; CALCOCO1; PRDM14; MEIS2; HAND1; KDM5B; PLAGL1; LHX3; YBX1; ZNF154; ZNF467; RING1; FOXH1; MYCBP; SP140; PRDM12; ARRB1; SPDEF; LZTR1; TFDP3; TSHZ2; HMGXB3; ZNF816; RBPJL; MAML3; ZNF93; PROP1; TBX10; HOXC5; SLC2A4RG; WWC1; CDIP1; SSX7; ARNT2; EHMT2; SIX6; AIRE; FOXE3; ZNF611; ZFP2; ERBB4; LHX6; NR1H3; POU6F2; TUB; BARX1; SOX11; CHD2; RORC; ACTL6A; TBX6; SOX3; MED25; TAF6L; ESR2; RFX3; CREBL2; PHOX2A; ATN1; FOXL1; HOXB5; ZNF682; NOC2L; NEUROD4; HSF4; TULP1; ZNF507; HESX1; PRDM9; SIM1; ALX3; NR5A1; IKZF4; PBX2; FOXN1; ZNF76; AR; NEUROG2; CD3D; HOXC8; FOXB1; NKX6-1; TBX19; DCC; ACTL6B; ESRRB; ZKSCAN8; ZNF215; NFIX; ZIC4; PHOX2B; ZBED2; ZBTB7C; CNBP; SOX14; KLF8; CSDC2; GBX1; ZNF671; ZNF44; ZNF136; RAX; ZNF32; FOXJ1; FOXD3; NR6A1; ZIC3; ASCL3; POU1F1; SRY; RARG; ZSCAN2; SHOX; EMX1; HIF3A; TBX21; HOXB13; NFATC4; ZNF606; CREG1; NAB2; AFF2; SUPT7L; SPI1; PAX1; IRF5; GLI1; SALL2; ETV7; CERS4; STAT2; HIVEP3; ZNF440; ZNF544; TFEC; IFNB1; ZBTB7B; CALR; PITX1; ZNF423; NHLH2; THRA; ZIM2; IRF3; USP16; HOXA3; HEY1; ZNF81; TCEA1; GTF3A; ZNF695; JAK2; TAF10; MXD3; NR2F1; FOXF1; WT1; KLF15; ZNF141; HNF1B; ZNF85; LIN28A; HOXC4; HSF1; SP140L; AEBP1; TP53; FOXN3; GRHL2; ARID5A; NEUROD6; NFE2L3; HDAC1; LMO1; EGR3; SOX5; ZNF33B; ZNF107; ARID3B; ZNF273; ZNF532; NKX3-2; PRMT2; HIPK2; SCMH1; ZFP69B; BPTF; FOXF2; PSMD9; FOXE1; ZNF675; ALX1; IRF8; ZNF43; NR4A1; MYRF; TEAD3; WDR77; MNX1; MNDA; IRF1; HMGN3; EGR2; SUPT4H1; PEX2; ZNF358; FOXL2; TFEB; NR5A2; ZNF512B; SIX3; TCF21; TOX; EYA1; VDR; ZNF331; ZNF83; OVOL2; ZNF195; ZNF580; ZNF721; ZFHX4; HOXB2; ZFPM2; CSDE1; HOXD1; ZNF239; ZNF160; PAX6; CEBPD; FOXO4; LYL1; HLX; LMCD1; ENY2; RFX2; GFI1; ZSCAN18; EHF; PBXIP1; ISL1; MEOX2; MXI1; ZNF562; TWIST1; TFDP1; BNC2; KAT6B; NCOA2; MYBL1; SSBP3; TRPS1; MEIS1; DMTF1; BATF3; GATA6; OLIG2; ZNF652; RFX5; TCF7; MYCN; SMAD6; ARID5B; HOXB6; TAL1; SOX10; WNT4; ZNF264; PPARG; MTA1; HMGA1; LOXL2; NKX2-2; BCL11A; IRF9; ELF5; FOSB; ESR1; TGFB1; DAXX; ZNF91; NR4A2; INSM1; BHLHE41
Down-regulation	221	MYC; TSC22D3; CRK; CDK7; FHL2; SOX4; KAT6A; CCNA2; XBP1; ABL1; HOXA5; FOXO3; TBP; SUZ12; BHLHE40; TSC22D2; SFPQ; CTCF; ADNP; CLOCK; USP22; SNW1; NCOA6; TOB1; NFKBIA; CNOT1; HES1; FOSL1; BCLAF1; RBM14; REST; MAGED1; IKBKAP; ZNF263; RNF4; TCERG1; HSF2; NPAT; ZFP36L2; HDAC2; VEZF1; SP3; TBPL1; DPF2; TSC22D1; SETD2; SMAD4; PSPC1; CHD9; TAF5; BTG1; ZBTB11; PURA; KAT7; ZNF302; TLE1; TRIM32; ING2; TAF9; CRY1; ZKSCAN1; DDX17; BRD3; MED6; UBE2I; SERTAD2; BRPF1; TULP4; TERF2; HIF1A; BAZ1B; PLAGL2; ZBTB7A; RNF111; WHSC1; ZNF189; PMS1; CEBPB; ATF5; AGO2; ZBTB18; MAX; RAD21; ARID4B; CHD1; MAML1; NLK; POLR2A; RYBP; ZNF146; JARID2; NRF1; ZNF227; SMARCA5; PQBP1; NFYA; PIAS1; ZNF281; PKNOX1; SAP30; MED27; SIAH2; SMAD7; CBX3; TOPORS; MED13; IRF2; ITGB3BP; RRN3; NELFB; CDK8; JUND; ZNF143; YAF2; NFIL3; NR1D2; PATZ1; YWHAB; HIVEP2; HNRNPD; MED21; ZBTB24; ARNTL; RNF6; ZBED4; SUV39H1; ZNF7; ARID4A; NAB1; CENPF; BASP1; CTR9; MED17; AATF; TSC22D4; BRD2; TFAM; TRIM27; ELF1; PPRC1; CBX5; ING3; ZMYM2; HMGXB4; PHF20; SMAD1; RLF; ZNF12; CTBP2; RUVBL2; NFKB1; RBBP4; CCDC59; MAFF; PUF60; MED1; ILF2; TMF1; BIRC2; MNT; ZIC1; TCF20; NR3C1; RERE; PNRC1; ETS2; TCF12; MBD2; MEF2A; UBP1; RARA; MKL2; AFF1; FOXO1; RNF138; ZBTB16; BRD8; RREB1; TRIP6; ATF2; AHR; CBFB; BTF3; TEAD4; NRIP1; BCL10; ERG; KLF9; ZBED1; KLF6; KLF4; ZNF131; TGIF1; ATF4; TBX3; SCAND1; PTTG1; CEBPG; JUNB; MYB; NFE2L1; HMGB3; NCOA4; SMARCA2; SOX9; HMGB2; DLX2; ID1; FOXG1; TRIM16; VGLL4; FOXD1; ELK3; KLF5; NR2F2; SATB2; KDM5D; IFI16; DACH1; KDM5A; NFATC3