Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12419 Geldanamycin GSE70138 HME1 Human 3h 0.37uM EID0018
Types Number Response transcription factors
Up-regulation 97 NR3C1; DDIT3; ZMYND11; CNOT3; XRCC6; PNRC1; EN1; RING1; ZNF248; KLF5; HEY2; TAF7; FOXF1; BACH1; ATF4; KLF3; TBX2; TFEC; CALR; SUPT3H; FOSL2; PAX6; ZFHX3; MYCL; FOXF2; TOB1; BCL6; TEAD1; CREB3L2; XBP1; FOXA2; PITX1; CITED2; LITAF; YAP1; MYF6; PROX1; HOXA10; HEY1; HLX; ZIC1; ZNF426; NR3C2; ZNF580; ARID5B; CNBP; ZNF124; TCF7L2; KDM5D; TFEB; ZNF175; FLI1; JUP; ZNF512B; HBP1; AHR; ZEB2; ID3; ZSCAN31; ISL1; ZNF652; NR1H3; CREBL2; CEBPD; TOX; HMGB2; ID4; ZNF232; SALL1; NR4A2; CREB1; TDP2; ETS2; MITF; TSC22D1; ZBTB38; HOXA11; TGFB1; INSM1; PBX3; SMAD6; TRIP6; TXNIP; FOXN3; SOX13; MNDA; ST18; MSX1; ATF3; ZNF91; ZNF165; ZBTB18; MECOM; TBX3; PBX1; ARNT2; SOX11
Down-regulation 51 FOSL1; TAF5L; SMARCD3; MNT; PPRC1; GATAD2A; GLI3; MAFG; ARID5A; HOXC6; WHSC1; ZBTB16; ESR1; NFIB; TSC22D3; EGR3; E2F3; KLF10; RNF138; ASH2L; RNF6; IRX4; TRIM22; REST; SMARCA5; BAZ1A; TAF10; FOSB; WT1; CITED1; RORA; BACH2; ZBED2; ZNF532; MLXIP; PHF20; HMGB3; CTNNB1; ZFP36L2; MYBL1; ELK3; IRX5; KLF6; MTF2; TFAP2C; TRIB3; ID2; EYA2; RUNX3; GATA3; IKZF1