Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12416 Geldanamycin GSE70138 HME1 Human 3h 10uM EID0018
Types Number Response transcription factors
Up-regulation 59 DDIT3; ATF4; TRIB3; IRF1; CREB3; ATF3; PNRC1; MAFF; RBFOX2; MEIS2; PPARD; ZNF232; PITX2; PLAGL2; VPS72; PRPF6; ZNF217; FOXK2; PBX1; CRY1; TULP3; MAFB; FOSL2; CEBPG; PCGF2; ZNF512B; ZNF331; MEOX1; ZEB1; HBP1; SOX9; CCNE1; SCAND1; MYRF; KLF4; TWIST1; PITX1; ZNF266; ZIC1; MECOM; ZNF423; NFIL3; ZFPM2; FOXG1; NR4A2; TEAD4; CALR; SOX13; MTF2; SOX11; HDAC9; SOX17; TFAP2C; AEBP1; EYA2; ZNF91; ARNT2; POU2AF1; EMX2
Down-regulation 46 HMG20B; VGLL4; ARNTL; GTF2I; PRKDC; FOXJ3; HMGN3; ZBED1; HOXC6; IRX5; NUP62; C1D; TP63; CBX3; SMAD3; HES1; TCEB2; ETS2; PHIP; HSBP1; SFPQ; HTATIP2; HOXA5; TRIM24; BAZ1A; ZMYM2; PURA; ENY2; NKX2-1; E2F3; BCLAF1; SATB2; TRIM29; LEF1; FOXA1; ID2; HMGB3; TOX3; ZBTB16; HOXC10; PTTG1; KLF6; TSC22D2; KDM5D; TXNIP; TCFL5