Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12400	Mitoxantrone	GSE70138	HME1	Human	3h	1.11uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	170	EGR1; STAT1; HLX; BRF2; RBPMS; SMARCD2; ZBTB39; ZNF552; LMCD1; ZBTB16; AFF1; SSBP2; ATF7IP; MYCN; PAX2; IRF1; WHSC1L1; ZNF710; SP1; SFMBT1; ZBTB24; POLR2A; TFE3; PIAS2; NR1I3; ZBTB48; ARID3B; ZBTB40; KAT6B; STAT2; DMRT1; NFIX; KDM5D; TWIST1; ARID3A; SSX1; DNAJC1; CREM; HOXA1; TSC22D3; TRIM22; THRA; LMX1B; ZFHX2; PHF8; ETV1; ZHX3; TRIM25; ZBTB25; ZMIZ2; PPARD; NR2E1; TBPL1; PROP1; MDM2; ZIC1; ZNF79; NSD1; ZBED1; OLIG2; SP140; CEBPA; DMTF1; FOXA1; ZNF506; YEATS4; ZFHX3; FUBP1; HLTF; FOSB; PBXIP1; PCBD1; CIITA; WHSC1; FOXJ1; LHX3; PIR; ZNF331; ZNF107; TRIP4; SKI; SSX3; MEF2C; SPDEF; FEV; CBFA2T3; BRCA1; HTATIP2; BLM; ZMYM2; MAFF; HIPK2; FOXF1; UIMC1; YBX2; RHOA; BATF; ZSCAN18; POU2F2; HSBP1; IRF4; PRDM2; ARID5B; ATF3; NPAS2; PPARG; ELF5; TERF2; EZH2; CEBPZ; ZNF394; SAP18; HES1; ST18; E2F8; GRHL2; FOXJ3; AIP; RBPJ; HDAC6; NR4A1; ZIC3; JAK2; SOX13; CBX6; ADRB2; ERBB4; NR1H3; ZNF274; NFKBIA; ZNF432; BMI1; ZNF239; ZNF721; FOXD1; MYCL; MECOM; FOXE1; MAFB; CUX2; ZMYND8; TAL1; KAT2B; CCNE1; MEOX2; SALL2; CREG1; FOXC1; CD3D; HDAC9; TCF12; MYB; ERG; ZNF423; KLF2; TCEA2; TFEC; KLF4; BHLHE41; SPEN; EGR3; RBBP7; RUNX3; HOXA11; FOXG1; ID2; EMX2; BASP1; TXNIP; IKZF1
Down-regulation	153	MYC; PDLIM1; FHL2; FOXO3; MED15; ZMIZ1; APEX1; HMGA2; FOSL1; LOXL2; SMAD3; TCERG1; NEDD8; CBX4; CEBPB; BCL10; RCOR1; HIRA; ARID4B; ERF; NR1D2; ATF2; TLE1; THAP7; RNF4; MTDH; UBE2L3; ZNF189; THAP4; KAT8; JUN; ARNTL2; BIRC2; MED14; ZFPM2; TRIM28; ZNF263; WT1; SOX9; ZNF7; KLF5; GATA6; ZBTB11; CCNC; ATF4; CBFA2T2; SNAI2; URI1; PEX2; ZBED4; NR3C1; ZNF12; CTBP1; CNOT3; NELFB; PNRC1; ATF5; FLNA; SRCAP; ZBTB20; PSIP1; HMGA1; SMAD1; PQBP1; BRD4; MAX; DEK; SLC2A4RG; CRY1; ID1; TLE4; TOPORS; ZNF112; ZNF45; RBFOX2; INSM1; ZNF302; PAX8; PTRF; ELF2; CARM1; SMARCE1; NRIP1; MED17; KLF10; FOXK2; PBX1; ZNF184; MYBL1; TRIM29; WNT4; ZNF266; ENO1; PROX1; ZFP36L2; NR2F2; FOXL2; TRIB3; ZFHX4; TFCP2; VGLL4; RNF14; TP63; ARID1A; ENY2; KLF13; JUP; ZNF148; CEBPG; PBX2; ZNF711; TGFB1I1; ZEB2; EHF; CAMTA1; BTG1; FOSL2; WWTR1; TEAD4; MTA1; DEAF1; BAZ1A; ARNT2; ZEB1; TCF7L2; CARHSP1; CEBPD; PEG3; OSR2; NKX3-1; BBX; ISL1; ZNF232; CHD9; TSC22D1; ETS1; ZBED2; LIN28A; SIM2; YWHAB; ID3; ZNF217; LITAF; ZFP36L1; CALR; TOX; ELK3; ZNF83; NR4A2; CREB1; MYRF; POU2AF1; TCFL5