Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12392 Chir-99021 GSE70138 HME1 Human 3h 10uM EID0018
Types Number Response transcription factors
Up-regulation 84 SUV39H1; BHLHE40; SAP18; FOSL1; ZFY; RUNX1; MAFF; EGR1; ZNF23; WIZ; HDAC6; PITX2; NR1H3; BPTF; THAP1; SIX6; ZNF107; TRIM25; COPS2; AIP; RHOA; GTF2I; EMX2; CBX4; ZNF580; RSF1; RUVBL2; IRF1; KDM5D; MEN1; SSBP3; GATA3; TERF2; SOX18; ATF4; NCOA3; SIN3B; RBFOX2; TFCP2; EGR3; CALR; TGFB1I1; KAT8; EGR4; ARID1A; ELF5; PATZ1; NR5A2; POU4F1; HOXD3; CREB1; FLI1; MEF2C; NR1H4; MECOM; MNDA; APEX1; NR4A2; E2F8; JUNB; SMARCA1; TCEA2; AR; ZNF91; INSR; SIX2; HTATIP2; NRIP1; ZNF467; FOSB; SUB1; BRD4; SREBF1; HOXC10; ERBB4; ST18; SMAD1; HOXB7; PITX1; BCL11B; NR1H2; CREG1; KLF9; TRIB3
Down-regulation 94 CNOT1; ADRB2; BCOR; USP22; PBX3; FUBP1; HMGA2; ZNF217; MED23; RCOR3; MEIS1; CBFB; PHF1; BAZ2B; ARID4A; CRY1; TLE4; ZNF160; CHD7; CHD1; ZNF721; PNRC1; PKNOX1; NCOA2; ZMYND8; UIMC1; ETV1; NAB1; DNAJC1; CTBP2; TBL1XR1; MTF2; FOXJ1; ZNF652; HOXA5; RREB1; ZNF84; SP3; TFDP1; ZBTB38; CHD9; SMAD3; BRD7; TLE1; ARID5B; ID1; ASCL1; ELF1; LMCD1; AHR; HSBP1; MAF; HMGB3; YWHAB; MXD4; DMTF1; PHIP; CTNNB1; ZNF329; ZNF423; AFF1; ZMYM2; SOX9; MXI1; HMBOX1; CEBPD; SCAND1; BRD3; INSM1; ZBTB20; TDP2; KLF6; ID4; LITAF; RUNX3; ETS2; ZFP36L2; ZBTB18; IRF7; FOXD1; MYBL1; TOX3; TRIM16; MAFB; BNC2; ZSCAN18; THAP11; DLX2; ID2; TCF4; ZFP36L1; CITED2; LEF1; ZNF586