Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12339 Azd-7762 GSE70138 HME1 Human 3h 10uM EID0018
Types Number Response transcription factors
Up-regulation 65 TSC22D3; HOXA5; SSBP2; BRD8; TAF5; NFIL3; ARID5B; HBP1; RAD21; SUV39H1; HOXA4; ARRB1; FLI1; PNRC1; SUPT6H; CENPF; MKL2; CBX3; RXRA; MAZ; PTRF; TWIST1; PBX1; AFF1; MEIS1; TXNIP; HOXD11; ZNF148; FOXM1; PITX2; ZNF304; TRPS1; KLF5; CEBPD; ZNF217; SLC2A4RG; TFAP2A; RBBP8; HOXA10; HMGB2; DEAF1; HOXD10; SREBF1; ERBB4; PBX3; HOXC10; WT1; POU2AF1; MECOM; TRIP6; JUP; CITED2; FLNA; HOXA11; OSR2; FOXG1; JUND; HOXC6; TEAD4; ZFPM2; THAP11; MEIS2; ARNT2; EMX2; TFAP2C
Down-regulation 61 FOSL1; HMGA2; MYC; JUN; FHL2; MAFF; SATB2; FOSB; LMCD1; PPRC1; ADRB2; REL; ABL1; CBFB; EGR3; NFKB1; ELK3; JUNB; SERTAD2; ZNF3; BAZ1A; ZNF107; SOX4; ETS1; BCL3; SMAD7; SMAD3; MAFG; CUX1; C1QBP; TSC22D2; CREM; BHLHE40; ETS2; NR4A1; SIX2; MLXIP; FOS; DMTF1; ZNF281; TAF1D; SPIB; VGLL4; HMGA1; ZBTB1; FOXD1; KLF10; SATB1; ZNF652; NRIP1; KLF6; TBX3; TSC22D1; WWTR1; ATF3; PAX5; EGR2; KDM5D; FOXC1; TOX3; IKZF1