Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12314 Gsk-1904529a GSE70138 HME1 Human 3h 0.04uM EID0018
Types Number Response transcription factors
Up-regulation 692 FOXO4; PAX8; ZNF701; NFKB2; RORC; LZTS1; SHOX; ZNF506; NFATC4; POU3F1; ZIM2; GTF2I; ETV1; ZNF273; ONECUT1; TAF7L; PRDM5; WNT4; CHD2; OLIG2; BRWD1; PRDM13; IKZF2; TEF; ZNF507; ZNF460; TBX4; SUV39H2; PHIP; MAML3; ZNF253; MTF1; ZNF778; THRB; NKX2-5; ZBTB6; ZNF671; ING4; CALCOCO1; PAX7; ZNF835; ZNF493; HMG20A; SETDB1; TAF4B; ZNF665; EBF2; PRRX1; TXNIP; ZNF287; STAT5B; SP140; ZIC4; WHSC1L1; FOXN1; ZNF141; POU2F3; ZBTB25; DDX54; POU6F1; ZNF212; ZNF675; PGR; HNF4A; ZFY; PAX4; PPARA; ZNF552; AFF2; HAND2; RFX3; CBL; PROX1; FOXE3; GLI2; CITED1; LHX2; ZNF549; ZNF783; ZNF711; ZNF85; ZNF83; SOX30; ZNF814; POU3F3; NR5A1; ZNF75D; HNF1B; IRF1; FOXL2; UBTF; ZNF480; ZNF177; PRDM8; PAX1; ZNF211; SOX5; HDAC11; GBX1; EYA3; ZNF324B; KLF3; NR3C1; ZKSCAN8; SCMH1; ZNF107; ETV6; TULP2; ZNF710; ELK4; ZNF224; ZNF74; LHX3; DLX4; ZNF282; ZNF550; ARNT; ASCL3; NKX3-2; POU3F2; ZNF80; ZNF174; RFX2; ZXDB; PLAGL1; GCM2; CIITA; ASH1L; ZNF407; SP1; ZNF440; GCM1; ZNF692; SNAI1; DOT1L; MEF2D; ZNF221; NEUROD1; ZNF516; POU1F1; MBD4; ZNF695; RBPMS; ZNF132; HSF4; AFF3; HEY2; SCRT1; TRPS1; VHL; ATOH1; ZNF674; GSC2; ZNF208; EGR3; LMO1; ZNF142; HNF1A; HOXC11; NEUROD4; ZNF442; HOXA4; MSC; ZNF157; HIC1; ZNF276; BACH2; GMEB1; MXD1; NR5A2; ZNF34; ZNF780B; ELF3; ASCL2; ZNF81; ZNF556; ZNF225; NRL; PDX1; ZBTB44; ZNF41; ZNF343; SSX7; OVOL1; SMAD9; TAF12; TBX19; ZNF236; KLF8; ARID3A; MSX2; AEBP1; MAFK; HOXB8; ZNF471; PBXIP1; ZNF76; POU6F2; GATA1; ZNF667; GFI1B; HES2; E2F2; FOXD3; TRIM25; LZTR1; ZBTB3; ZFP37; CSDC2; ZNF415; ZNF7; POU4F2; ZNF337; BRDT; HOXA2; FOXH1; ZNF419; ZNF254; MDM2; ZFP2; TBL1Y; ZNF197; FUBP1; TAF1; TFDP3; CBX8; MED12; EP400; POU3F4; FOXO1; ZNF234; TULP1; ZNF606; SP4; BTG1; TSHZ2; SRY; VGLL1; CAMTA2; EMX1; ZNF426; DCC; POU2F1; ZNF135; ZNF214; PRDM9; RARA; NR6A1; ZKSCAN1; ZNF133; TFAP2B; RERE; SSX1; SOX14; ZNF510; FOXD2; MLLT1; LHX6; SOX21; NR2E1; ZNF304; HNF4G; ZNF235; RHOA; BCL6; THAP9; ETV5; KAT2A; ZBTB39; TBX21; FOXB1; ZNF248; TBR1; ZNF14; BRF2; BNC1; PAX3; MYOD1; CARF; GLI1; CRTC1; BHLHE41; ZBTB7C; RFX1; CBX2; TP73; RSF1; JAK2; MEOX1; ZNF257; ZBTB17; PKNOX2; ZNF43; ZNF813; ZNF749; IKZF3; LYL1; ZNF134; ZNF682; PML; TRIM33; ZNF672; ZNF443; ZNF391; MYCN; ZNF446; ZNF362; MYF6; ALX4; SPIB; ZNF787; PHF8; NR1I3; SIX3; ZNF528; SP2; RUNX1; CREB5; RAX; ZNF696; VENTX; HIC2; ZNF329; CBFA2T3; HOXB1; BACH1; KMT2D; HIPK2; TLX3; CIZ1; PRDM10; EHMT1; IKZF5; MED31; YBX2; ZBTB14; SIX6; ZNF324; STAT2; PRDM12; WWP1; MAP3K10; ZNF79; TLE2; CIR1; ZNF227; ZNF154; MEOX2; ZBTB7B; ATF7; TFAP4; ZNF613; ZNF223; GATA4; ZNF688; FOS; ONECUT2; HTATIP2; APBB1; AFF4; ALX3; NEUROG3; MLXIPL; ZNF91; ZNF816; ZEB1; MED15; PKNOX1; ETV2; FEV; ZNF264; ZNF136; HAND1; ELF2; IKZF4; SMARCD3; CREB3L2; KLF10; RARG; PLAG1; CDX4; MNX1; NR3C2; ZNF180; AIRE; FOXE1; OVOL2; PAX9; CBX7; SUPT6H; GFI1; TADA2A; CHD8; TRIP11; ZNF117; TFEC; ZNF484; ZNF16; CDIP1; ZSCAN32; SOX9; HLF; HDAC5; ZHX3; PITX3; SNIP1; MAPK8IP1; TBX5; GRIP1; BAZ1B; MXD3; TRIP4; ZBTB20; ZNF334; HOXC5; ZNF551; HEYL; BARX1; ZNF764; ASCL1; EN2; ZNF492; LBX1; TRAK1; RFX7; ZNF768; NR1H4; TAF9B; REPIN1; HOXD9; HOXD12; ZNF467; ZNF10; CERS4; IRF4; USP21; FOXI1; NKX6-1; BARX2; PEG3; ZSCAN18; TSC22D3; THAP3; CEBPA; DMRT1; CRYM; EYA1; MED20; TAF6L; NCOA2; HR; POU4F1; ZNF267; TTF2; IFNB1; HMX1; ARRB1; ZNF586; IRF9; DLX5; PRDM1; PROP1; TAF1C; NR0B2; NR1D2; FOXA2; SERTAD2; SOX1; KLF15; KLF4; KAT7; FLI1; ZKSCAN4; PRDM16; RBPJL; NEUROG2; PRDM2; NFATC1; EZH1; PAX5; ZNF44; ESR2; HOXC10; GRHL2; LMCD1; CBX4; ZSCAN9; MDM4; FOXG1; REL; ZKSCAN7; MED14; POLR3C; NEUROD2; NHLH1; FOXN3; ZNF274; KLF1; ZBTB32; HOXA5; ZNF250; ZNF222; GON4L; NFYC; HOXB5; IKBKAP; SPDEF; UBE3A; OSR2; ZNF175; BAZ2A; RXRG; HSF2; RFC1; ZIC1; YEATS4; PATZ1; TFCP2L1; ATF7IP; ZNF611; NFAT5; SIRT7; CUX1; ZNF8; TRAF6; L3MBTL1; ZNF200; FOXC2; HOXD13; UIMC1; GLI3; ZNF219; TLX1; ZNF124; RING1; SOX17; NR4A1; SND1; ID4; CHD3; E2F6; CXXC1; ZNF266; FOXC1; PIAS1; KDM5B; ZNF226; STAT5A; PCGF3; KAT6A; KDM5C; ZNF350; IL16; ERF; HEY1; BATF3; NPAS2; ZNF468; BLZF1; ZNF33B; CREB3L1; SOX3; TSC22D4; UTF1; EGR2; ZNF155; MITF; NFIX; NFX1; ZNF112; HOXB2; BRIP1; SMAD5; NHLH2; MEIS1; SOX4; KAT2B; CUX2; URI1; IRF5; TAF1D; PRMT2; NAB2; HESX1; ZNF12; SIAH2; CDX1; ELF5; ZNF184; HHEX; MYT1; ARID4A; DBP; TFCP2; ZNF93; RCOR1; SALL2; MTA1; TBL1X; SMARCC2; BATF; HOXA11; NANOG; ZNF654; CCNT1; LEF1; EYA2; ZIC3; NFE2; ILF2; ZNF573; HOXD11; STAT6; NLK; PRPF6; BCL11A; KAT8; ING3; SHOX2; EZH2; MSX1; KLF6; HLTF; LPIN2; BCL3; ZFHX4; NCOA1; NFATC3; ZNF587; TAL1; EGR4; ZNF430; TFEB; SOX11; SATB2; CREM; MLXIP; HMBOX1; TRIM24; FOSB; RORA; ZNF160; KLF13; BHLHE40; ATF3; HMGB2; HIPK3; NR0B1; INSM1; SOX13; SALL1; SIX1; ZSCAN16; RNF141; ESRRG; SIX2; MNDA; SLC2A4RG; TCF12; MED1; CAMTA1; TCF7; TGIF1; BNC2; DMTF1; TP63; PITX1; ZNF217; NRBF2; FOXF1; MYT1L; HDAC9; TCF7L2; IRF7; CITED2; NR4A2; MECOM; TBX2; GATA2; HOXA10; STAT4; BMI1; MEIS2; HMG20B; KDM5D; MYB; ZFP36L2; CREG1; WT1; POU2AF1; BASP1; TCFL5
Down-regulation 137 ATF1; PA2G4; RNF6; ARID5B; TFDP1; CBFB; MYBL2; TERF1; TBP; CTBP2; ZMIZ1; CREB3; HNRNPD; STAT1; PSMC3IP; BTAF1; PHF20; HMGA2; TRIM27; RBM39; ERBB2; SF1; BRCA1; ITGB3BP; PSIP1; COPS5; MED27; SFPQ; MLX; FOSL1; RBBP4; MXI1; BIRC2; WWC1; SMAD7; YAP1; ZNF410; CNOT1; ENO1; RNF4; FOXK2; CEBPB; USP22; AHR; PCBD1; RUVBL2; CRY1; ZNF281; CDK8; CBX3; SREBF1; HMGB3; COPS2; ARID4B; ELF1; BCL10; ENY2; BRD3; RBBP8; PIAS2; TCEA1; THAP10; PTTG1; SETD3; CEBPZ; AATF; HMGA1; TLE1; TFAP2A; MBD2; THAP4; ADRB2; SUPT3H; ZZZ3; ZNF131; NR2F6; CDK9; AGO2; ZNF354A; TAF9; YWHAB; TDP2; VDR; YBX1; TOX3; ZMYND8; TCERG1; TGIF2; TAF11; BRD8; RNF138; NR2C1; JUND; SMARCC1; MAFG; CTNNB1; RYBP; NFE2L1; NFIB; ZNF148; ESR1; BBX; JUP; TCEB2; HIVEP1; FOXM1; CCNC; CEBPG; KAT6B; BANP; NAB1; HMGB1; TOX; IRX5; ZBTB1; HMGN3; ZFP36L1; ELK3; ID3; SAFB2; NRIP1; NKX3-1; JARID2; MNAT1; BAZ1A; PCGF2; SCAND1; TSC22D2; DLX2; HOXB7; IFI16; DACH1; SPEN; FLNA; CALR; ID1; EMX2