Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12304 Bms-387032 GSE70138 HME1 Human 3h 3.33uM EID0018
Types Number Response transcription factors
Up-regulation 121 SUV39H1; DAXX; AFF2; MED12; KDM5A; ELK1; LHX6; ZIC3; PLAGL1; MED14; DLX4; HDAC5; SOHLH2; ZNF711; ZNF248; MLXIPL; NR5A2; PAX9; NEUROD1; RAD21; TBX1; ZNF107; BARX2; UBTF; MBD4; DMTF1; KAT2A; KDM5C; SOX18; ING4; BRWD1; TERF1; PRDM14; ZNF606; PAX6; EHMT2; ZNF665; NFIX; YBX2; MMS19; BCL11A; VGLL1; LHX3; PRRX1; ONECUT2; ZNF721; PRMT2; DBP; ZNF611; ZNF177; ZNF536; ZNF32; SIX3; ZNF160; JUP; SSX1; PITX2; AES; OVOL1; TTF2; HOXD1; MLLT10; HESX1; CALR; ZNF33B; NKX2-2; L3MBTL1; TWIST1; ZNF91; HOXD3; MYCL; TFEC; SOX2; AEBP1; NR0B1; EZH1; MXD4; CBFA2T3; HDAC6; CNOT3; GTF2I; MTF2; ZIC1; NFE2L3; PSIP1; PRPF6; PQBP1; ZNF43; CARHSP1; CCNC; NFATC4; BATF3; CERS4; ZNF544; ZNF117; HSBP1; ZKSCAN1; PITX1; TCF4; NR1H4; ZNF587; ZSCAN18; KAT2B; NR1H3; HLF; TOX3; DLX5; DNMT3B; TCF7; SPIB; PAWR; RBBP7; TCEA2; IRF8; ZBTB18; SOX17; INSM1; TRIM22; NR4A2; CITED2; ARNT2
Down-regulation 139 MYC; FOSL1; NFKBIA; CEBPB; ADRB2; FHL2; RELB; HMGA2; JUN; E2F6; PLAGL2; GMNN; SNIP1; FOXO3; RLF; NFIL3; CRY1; SF1; CEBPG; GMEB2; NRIP1; CDK7; TBP; VEZF1; SNAI2; HIVEP1; SRF; SNW1; HES1; FOSL2; TGS1; SOX4; ZBTB11; XBP1; NR3C1; HOXA5; RERE; ZFP36L2; NFKB1; AFF1; RNF138; PHF2; CHD1; SOX9; JUND; SERTAD2; KDM2A; SMAD3; SP3; FOXD1; BCL10; ARID4B; CEBPD; ADNP2; ELF4; KAT6A; CHD7; BHLHE40; FOXJ3; BIRC2; PTRF; SATB2; SMAD7; ZNF45; ZMIZ1; MNT; ELF1; MAFG; ARID1A; FOXK2; TRIP4; RREB1; RSF1; TSC22D3; ZBTB7A; MED17; VDR; RNF6; ZNF217; DDIT3; HDAC4; RELA; MAFB; KLF7; RXRA; HOXB6; ING2; NKX3-1; FOXC1; RYBP; NRBF2; NUP62; NCOA6; HOXA11; FOXO1; ZNF267; KLF2; BCL3; ZBTB1; TFAM; ING3; CITED1; RORA; SIX1; E2F3; ARID5B; DLX2; BAZ1A; ZFP36L1; RBBP8; ZNF593; BHLHE41; ZBED2; ASCL1; KLF10; ZBTB38; PCGF2; BTG1; MED1; ELK3; TGIF1; BRD4; EYA2; TRIM16; SMAD1; SPEN; BRD2; PBX3; HMGB3; BMI1; HMGB2; TBL1X; SATB1; BASP1; KDM5D; AHR; FLNA; TCFL5; IKZF1