Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12302	Canertinib	GSE70138	HME1	Human	3h	0.04uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	THAP7; ZNF268; ELF4; ZNF34; SOX18; ZNF75D; HIRA; WNT4; TFAP2A; ZNF500; ZNF3; ZSCAN32; CEBPD; ZFPM2; ING4; HINFP; DAXX; DMTF1; KAT2B; RFX5; HHEX; ZNF217; NEUROD1; PCGF3; KLF11; PHIP; ST18; JUP; ZNF623; HIC2; MEIS2; ZIC3; PIAS1; TRIM24; NFIB; PBX1; ZMYND8; CSDE1; TSC22D3; VPS72; NR5A2; ZNF711; KMT2A; NANOG; ZNF304; TULP3; NFATC4; NR1H4; TRIB3; ZBTB16; SOX17; ZBTB20; ARNT2; INSR; ZNF232; IRF9; TCEB2; SALL1; MYBL1; SMAD1; CTBP2; WT1; ERBB4; ZNF544; BCL11A; CUX2; BACH2; PSIP1; ZHX2; ZEB1; LIN28A; ZNF423; ID3; CARHSP1; OSR2; MITF; ID1; TSC22D1; IRF8; BNC2; TEAD4; TOX; HDAC9; ELF5; DLX5; EMX2; HMG20B
Down-regulation	68	MYC; FOSL1; HMGA2; SIX1; SOX9; ZBTB43; NFYA; HIPK3; TRIM25; NCOR2; GTF2I; FOXC1; ATF1; MAX; ETS2; ETV1; RHOA; RUNX1; IRX5; PPARGC1A; ARNTL; NFKB1; SMAD2; NKX3-1; MEF2A; BHLHE40; NR1D2; SIX2; SATB2; SMAD7; SFPQ; EDF1; NCOA1; NRIP1; CTR9; EGR3; NPAS2; TOPORS; SIAH2; ETS1; FOXD1; MAGED1; AES; ZBTB38; TFAM; CRY1; KLF2; BAZ1A; ELK3; ZEB2; FOXJ3; SMAD5; HOXC6; CHD7; FOSB; ASCL1; NR4A2; KLF5; JUNB; TRIP6; ZIC1; CALR; BMI1; HEY1; MED1; THAP11; TRIM29; KDM5D