Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12300 Canertinib GSE70138 HME1 Human 3h 0.37uM EID0018
Types Number Response transcription factors
Up-regulation 43 TSC22D3; CSDC2; NFE2L1; NR1D2; TOB1; EPAS1; FOXN3; SPIB; HMGB2; DDIT3; ACTL6B; NR5A2; ATF4; SMARCA2; CITED1; CENPF; PITX2; TDP2; AHR; CD3D; FOXF2; FOSL2; TGIF1; MYT1L; TRIB3; NR2F2; SUB1; MYRF; CRYM; HOXB7; PAX6; NANOG; SAP30; AEBP1; HEY1; TLE1; OSR2; HOXC6; ID3; THAP11; BASP1; ARNT2; PEG3
Down-regulation 40 MYC; HMGA2; FOSL1; SATB2; JUN; ZMIZ1; EGR3; PLAGL2; BTAF1; ZNF107; EGR1; MED21; MAFB; NRIP1; FOSB; MLXIP; ZNF432; MSX1; ELK3; SMAD7; TRPS1; EGR2; ZEB1; TGFB1; BMI1; CHD7; CBFB; ERG; MYB; ZIC1; JUNB; CREB1; ZBTB20; BHLHE41; ETV5; MAGED1; LEF1; MECOM; HOXA10; IKZF1