Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12299 Canertinib GSE70138 HME1 Human 3h 1.11uM EID0018
Types Number Response transcription factors
Up-regulation 32 TSC22D3; ATF4; XBP1; DDIT3; BRD8; NFKBIA; GLI2; TRIB3; SCAND1; NFIL3; SREBF1; NR2F2; JUP; SMAD1; MEIS2; PBX1; ZFPM2; PSIP1; PIR; EMX2; BNC2; ATF3; TCEA2; MEIS1; MECOM; HMGB2; CARHSP1; LOXL2; CITED2; PEG3; ID1; ESR1
Down-regulation 31 HMGA2; MYC; FOSL1; SOX4; ZNF107; VPS72; CEBPZ; TEAD1; TBX3; ABL1; HSBP1; CHD7; ETS2; FOS; SKI; NKX2-1; ZFP36L2; JUNB; SOX9; ZNF22; SMAD7; ERG; NKX3-1; KDM5D; SATB1; MYB; TXNIP; FOXC1; LEF1; TCFL5; HOXA10