Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12295 Afatinib GSE70138 HME1 Human 3h 0.12uM EID0018
Types Number Response transcription factors
Up-regulation 29 TSC22D3; SAP18; NCOA4; CEBPA; MEIS1; ZNF12; TLE4; PLAGL1; EHF; DACH1; TLE1; WWC1; NR2F1; KDM5D; ETS2; FOXN3; TCF21; HMGB3; TRIP6; GATA6; SMAD6; FOXF1; RUNX3; SPEN; WT1; BASP1; ZFPM2; TBL1X; TOX3
Down-regulation 37 FOSL1; MYC; HMGA2; EGR1; EGR3; PRRX1; HOXC10; MAFF; ABL1; AEBP1; HMGA1; BACH1; MAFG; MDM4; ZNF654; CCNT1; HOXC6; NKX2-1; TGFB1I1; JUNB; STAT6; CD3D; JARID2; NR0B1; CRYM; SOX10; SALL2; NANOG; HEY1; NR4A2; TSC22D2; ESR1; ASCL1; THAP11; TXNIP; MSX1; HOXA10