Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12294	Afatinib	GSE70138	HME1	Human	3h	0.37uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	71	TSC22D3; PITX1; THAP10; NR2F1; ZIC1; NR3C2; PLAGL1; TBX2; ZSCAN31; NR1D2; HMGN3; TGFB1; MAZ; CRYM; FOXF1; WWP1; ADNP2; DLX4; ELF3; TRIP6; HLF; ARID4A; TFEC; RBPMS; BLM; APEX1; CAMTA1; TRIM22; ZNF33B; TLE2; CBX5; DEK; MYT1L; AES; ESRRG; TRIM16; KLF9; FOXF2; PPARGC1A; SMAD1; CTR9; ID3; SAP30; BHLHE41; MEIS1; ISL1; ING3; KLF5; TOX3; PSIP1; MYCL; ID4; ZNF512B; NFIB; TLE1; SMAD6; CREB1; DEAF1; FOXN3; ATF3; PAX6; DACH1; ST18; SOX11; NKX2-2; SALL1; PIR; TCF4; BASP1; HEY1; ID1
Down-regulation	58	FOSL1; MYC; HMGA2; BCL10; TGIF2; PPRC1; EGR1; CHD1; RNF6; CCNT1; VDR; ESR1; IFI16; CCNH; SP110; ABL1; ETS1; CDK8; ZNF654; PHF1; MAFG; EGR3; NR2C1; ZNF281; ZNF217; FOSB; ZMYND8; CREM; SP100; CNBP; PFDN5; SMAD7; RYBP; CTNNB1; HMBOX1; RORA; ERG; FOXD1; E2F3; NPAS2; RBPJ; BACH2; IRF7; WT1; TFAP2C; SOX10; BNC2; STAT4; ELK3; HMGB3; TBX3; MYB; LEF1; ZFP36L1; EMX2; GATA3; HOXA10; TCFL5