Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12292	Afatinib	GSE70138	HME1	Human	3h	3.33uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	MYCL; TSC22D3; ZSCAN31; TBX1; ZNF32; KLF4; STAT1; PSMC3; THAP10; ZNF219; NR3C2; CEBPD; PROX1; NKX3-1; EHF; ZZZ3; ZFHX3; BHLHE41; SOX17; ETS2; FLI1; CREBL2; FOXF2; ZNF189; NFKBIA; ZIC3; ZNF12; HOXB13; FOXN3; ZIC1; ZNF302; FOXF1; PITX2; TRIB3; ARID5B; FOS; SMAD6; CEBPG; ZFPM2; MYCN; MTF2; PSIP1; HOXD1; ZNF22; ZNF232; ST18; MEOX2; PIR; PBX3; NFIL3; EGR2; CUX2; TLE4; KLF11; MAFB; TRIM29; PAWR; ERBB4; TFAP2C; ID3; DACH1; ARNT2; MNDA; MYB; MECOM; NR1H2; TOX3; GATA6; TXNIP; THAP11; ID1; ID4
Down-regulation	46	MYC; HMGA2; FOSL1; ZMIZ1; KDM5B; UBE2I; RNF6; ATF1; MED4; CHD7; HSF2; NR2F6; ELF1; TEAD1; CUX1; SP100; SMAD3; ETV5; SIX2; NRIP1; MAFF; ZNF281; KLF10; PAX5; BCL3; EGR3; TGIF1; TRPS1; TOB1; NLK; CREB3L1; TGFB1I1; NCOA1; IRF8; IRF4; SOX9; NR4A2; PITX1; IRX5; RBBP8; ELK3; MAGED1; FOXC1; KDM5D; HOXA10; IKZF1