Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12291	Afatinib	GSE70138	HME1	Human	3h	10uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	36	TSC22D3; DAXX; DDIT3; ATF4; XBP1; STAT1; ATF3; IRF1; BRCA1; CEBPD; NFKBIA; ITGB3BP; TRIB3; ZNF32; ZFPM2; NR2F1; UBE2B; PITX2; NFIL3; CAMTA1; APEX1; NEUROD1; ERBB4; SCAND1; ZNF423; STAT5A; JUP; ST18; TRIM16; GATA6; HMGB2; PITX1; PEG3; CREG1; MEIS2; KDM5D
Down-regulation	51	MYC; HMGA2; BCOR; SATB2; AGO2; FOSB; PPRC1; REL; EGR1; ZBTB43; OLIG2; GATAD2A; MAF; BAZ2A; CCNT1; NR3C2; NKX2-1; EGR3; SMAD7; ETS2; KAT6A; TOPORS; CREB5; KLF13; CHD7; ZBTB1; SFPQ; NFAT5; FOS; ERG; SKI; SSX1; CBFB; ZBTB20; SIX2; MYB; FOXO1; TGFB1; THAP11; AR; DLX2; ZNF721; KLF9; HOXC10; BBX; RUNX3; NR4A2; TSC22D2; FOXC1; TCF4; EGR2