Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12260 Palbociclib GSE70138 HME1 Human 3h 0.04uM EID0018
Types Number Response transcription factors
Up-regulation 43 E2F2; BHLHE41; VGLL4; SMARCD3; HOXD3; RNF138; ZBED4; POU4F1; SMAD2; KAT6B; ZMYM2; TRIM29; CHD4; JUP; YEATS4; NFIB; DNAJC2; HLTF; PIR; FOXF1; PCGF2; HOXD1; ID3; BRD4; TGFB1I1; SMAD1; MLXIP; TCF21; ARNTL2; MECOM; GTF3A; ELF3; ZBTB16; IFI16; MYRF; WWTR1; WT1; ZNF165; PITX1; HOXB7; SOX17; FLNA; MEIS2
Down-regulation 25 UBE2I; PSMC3IP; SLC2A4RG; HTATIP2; CHD8; ZBTB18; BRD7; CTBP1; ZBTB20; TCEB2; DLX2; TFEC; DNMT3B; RXRA; JUND; IRF7; NFE2; PURA; LEF1; THAP11; BASP1; TXNIP; INSM1; CREB1; HOXA10