Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12223 Fostamatinib GSE70138 HME1 Human 3h 0.12uM EID0018
Types Number Response transcription factors
Up-regulation 22 HOXA5; BRD8; ZNF443; NR1D2; ID2; ID3; JUNB; CBFB; ING2; TXNIP; BCL3; FOSL2; REPIN1; PURA; SMAD6; CALR; NR2F1; TBX3; ID1; THAP11; KDM5D; PEG3
Down-regulation 35 PSMC3; SHOX2; NR5A2; MED17; NR4A1; FOXF2; BACH2; PAX6; KLF4; IL16; ELF3; MEIS1; TRIP6; TFAP2C; STAT6; IRF6; IRF4; SIAH2; CTBP2; DACH1; FOSB; BASP1; PAX5; SCAND1; HOXA11; STAT4; OSR2; ESR1; ATF3; KLF6; NR2F2; HOXB2; POU2AF1; EGR2; LEF1