Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12221 Fostamatinib GSE70138 HME1 Human 3h 1.11uM EID0018
Types Number Response transcription factors
Up-regulation 19 EGR1; TSC22D3; ELF1; HOXA5; NEUROD1; ZFPM2; ZEB1; TXNIP; NFIB; TOB1; TP63; PEG3; WWTR1; IFI16; BHLHE41; KLF2; ST18; NR2F2; MEIS2
Down-regulation 26 ADRB2; LMCD1; ZNF226; ETS2; SMAD7; CREB5; KAT6B; CRYM; IRF9; SIX2; NKX2-1; SMAD6; SIAH2; LITAF; OSR2; IRX5; E2F5; EHF; SOX9; DACH1; AHR; EMX2; MSX1; ZNF586; TCFL5; IKZF1