Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12216 Gsk-1059615 GSE70138 HME1 Human 3h 0.37uM EID0018
Types Number Response transcription factors
Up-regulation 99 PAX8; CDC5L; TSC22D3; RFX5; E2F2; SMAD2; TFCP2L1; HNF1A; ID3; TOB1; NFKBIA; SOX4; HOXC6; HDAC1; SETD3; GATA3; EGR1; ZNF217; RBPMS; KDM5D; CSDC2; PITX3; STAT1; NFATC3; RBBP7; TULP4; EZH1; RARB; NR2F2; KLF4; CDIP1; FEV; PRRX1; CDX1; FOXF1; LHX6; MBD2; TCF20; YBX2; CARHSP1; CREB3L2; IKZF1; PNRC1; SMARCE1; MYCN; HOXC10; GATA2; SMARCA1; FOSB; MECOM; CSDE1; KLF13; SLC2A4RG; HLF; FOXE1; HBP1; ISL1; MEOX1; CD3D; HMGB2; OSR2; DNAJC2; BRD2; TRIM24; SOX9; KLF2; CENPF; CBX7; ERBB4; YBX1; AFF1; PBX3; ZMYND8; CTBP2; TSC22D1; PHOX2B; ZNF91; IRF6; TCF21; PEG3; LITAF; NFAT5; TCF7; PAWR; KLF7; JARID2; ZBTB38; NFIL3; TBX3; MSX1; TRIM22; MEIS1; KLF6; TXNIP; ID1; DLX5; TBL1X; SALL1; TOX3
Down-regulation 78 NEDD8; PPRC1; SF1; MED27; ZMIZ1; BHLHE41; POLR3F; TERF2; SMARCD3; IRF3; TCEA1; EED; TRAK1; NFYB; CHD1; ZNF32; ZNF189; FOSL2; CREB3; MLX; AES; ZNF432; ZFX; PIAS4; ZNF468; HMGA1; NPAS2; HTATIP2; MTDH; TGIF2; MAFF; MNDA; UBE2B; RFXANK; MED21; CREM; INSR; MEF2A; CHD7; MED13; CBFA2T3; ZNF576; ENY2; EGR3; SUPT4H1; TLE2; E2F3; C1QBP; EHF; KAT6B; ZNF593; EDF1; BNC2; MYRF; HLX; SOX11; ATF4; PITX1; TFAP2C; KLF10; KAT2B; SIX2; ZNF331; TGFB1; ZNF551; ZBTB20; BAZ1A; IRF7; SALL2; MEIS2; ETV5; YWHAB; SMAD1; EMX2; ZFP36L1; EGR2; NR4A2; POU2AF1