Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12192	Alvocidib	GSE70138	HME1	Human	3h	1.11uM	EID0018

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	XRCC6; ACTL6A; IRF3; SSBP2; ZNF248; KAT2B; TTF2; HOXB13; SIX6; ZIC3; SCMH1; NHLH2; TCF25; SOHLH2; EHMT2; TWIST1; CALR; CERS6; STAT1; ZMIZ2; RBFOX2; ZNF219; BCL11A; NEUROD1; PLAGL1; HLTF; NR0B1; GLI2; ISL1; NR5A2; CSDE1; SMARCA1; SHOX2; ZIC1; HDAC9; PSIP1; PBX1; MEIS2; MEOX2; HDAC6; DEK; GTF3A; FOXF1; TCEA2; SLC2A4RG; FOXF2; PCGF2; SALL2; MTA1; MAF; IRF8; PAX6; MYBL1; EYA1; E2F5; TCF4; SATB1; AEBP1; CREG1; SOX11; MAGED1; HOXB2; PIR; MNDA
Down-regulation	149	MYC; FOSL1; NFKBIA; FHL2; ELF1; RELB; SUV39H1; ZBTB43; MAFG; NFIL3; SERTAD2; XBP1; CHD1; SMAD3; MAFF; ABL1; AGO2; CEBPG; MXD1; TFCP2L1; FOXO1; ETS2; ZMIZ1; PPRC1; GMEB2; KLF3; TGIF1; IRF1; CEBPB; NRIP1; MAFB; CEBPD; ARNTL; BHLHE40; ZNF212; SOX9; ZFP36L2; BCL10; REST; ZNF281; TSC22D2; HIC2; RNF138; ZBTB38; TOB1; RREB1; ZBTB16; RLF; RNF111; NFKB1; VEZF1; HOXA5; ARID5B; USP22; BTG1; ZNF211; NPAS2; TRAF6; REL; FUBP1; BIRC2; HES1; BRPF1; SFPQ; RBM39; PLAGL2; JUNB; ZBTB1; TBX3; PBX3; GABPB1; INSR; ERF; CCNT1; NFATC1; DAXX; RYBP; TSC22D3; KLF5; E2F3; RNF6; MED17; SNAI2; BRD8; ZNF394; ADNP; ELF3; PROX1; PSPC1; CHD7; TRIM29; BCL3; YWHAB; MNT; TRIM32; DDX5; HIVEP2; CRY1; ERG; DDIT3; SP100; ING3; BAZ2A; ATF3; NUP62; UBE2B; BASP1; FOSL2; NKX3-1; SMAD7; MTF2; NR1D2; ATF5; JUND; KLF4; TCF7; BAZ1A; CREB3L2; ZNF140; ETS1; KLF13; NCOA2; PPARGC1A; HMBOX1; NRBF2; KLF9; TLE4; ZNF432; EGR3; EDF1; ZNF264; ZNF160; KLF6; FOXJ3; ZNF721; AHR; KLF10; TRIP6; FOXC1; PHF20; TP63; MYB; ID1; EGR2; ELK3; HMGB2; POU2AF1; PEG3; IKZF1