Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12191 Alvocidib GSE70138 HME1 Human 3h 3.33uM EID0018
Types Number Response transcription factors
Up-regulation 58 MED15; SMARCD3; MED16; DBP; ZNF226; CNOT3; FOXJ1; EHMT2; ZNF611; XRCC6; HLTF; SMARCC2; ZNF652; STAT1; GTF2I; TGFB1; ZNF467; HOXB6; CREB3L2; SMARCB1; HMGN3; PIAS3; ID2; HOXB2; TLE2; CTBP2; HOXB5; REPIN1; CTR9; GTF3A; TRIP6; MECOM; ZNF91; SLC2A4RG; NR2F2; PAX6; ERBB4; AES; DEAF1; IRF8; PSIP1; NR2F1; ZNF160; GRHL2; SREBF1; EYA1; MAGED1; ZBTB18; HOXC10; ZFPM2; TBL1X; LEF1; FLNA; TCF4; CREG1; EMX2; ZSCAN18; ID4
Down-regulation 167 MYC; FOSL1; NFKBIA; ADRB2; CEBPB; FHL2; JUN; SUV39H1; BCL10; JUNB; BRPF1; RELB; SOX4; HMGA2; ZNF410; MAFF; PLAGL2; ZFP36L2; NFIL3; GMEB2; SNIP1; E2F6; TAF5; RLF; CHD1; SERTAD2; TRIM27; HES1; NRIP1; MAFG; ZFP30; PPP1R13L; MSC; ARID4B; NRBF2; SMAD3; BCOR; ELF1; BTG1; TSC22D2; ZNF324; XBP1; ATF7IP; ADNP; ZBTB1; ZMIZ1; CCNA2; NFKB1; BRF2; ELF4; ZNF184; MED17; MED27; POLR3F; ZNF443; GABPB1; MED6; NCOA4; HCFC2; UBE2I; CEBPD; TOPORS; PCGF1; TRAF6; ZBTB11; FOSL2; ZEB2; BAZ1A; FOSB; AGO2; ZBED1; ZNF292; BLZF1; CRY1; ZNF189; PNRC1; HOXA5; GLI3; FOXD1; SOX10; ZNF3; EGR3; ZNF281; HDAC4; ZBTB43; CDYL; MAML1; YWHAB; FOXO1; MAX; KLF7; SMAD7; ZNF432; ARID5B; BRD2; DR1; KLF4; SATB2; ATF4; ABL1; RORA; NAB1; NR4A3; BACH1; TRIM32; SNAI2; ZBTB16; TSC22D3; RNF6; RREB1; STAT5A; ALX1; ARNTL; ZNF394; PTRF; PRDM1; ZNF654; KAT6A; E2F3; FOXJ3; ZNF267; ZNF302; TP63; TRIM29; DAXX; RCOR1; JARID2; CEBPG; ING2; AFF1; BRD3; PURA; CHD7; CREM; JUND; ZNF304; MED1; KLF6; SKI; BACH2; GATA6; BATF3; ZNF134; HMGA1; SPIB; KLF11; MTF2; SAP30; BASP1; TBX3; ZNF217; RUNX3; ZNF331; EGR2; TRIM16; BCL11B; IFI16; TFAP2C; TOX; KLF10; INSM1; ATF3; NR4A2; EYA2; WT1; ZNF586; IKZF1