Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12173 Withaferin-a GSE70138 HME1 Human 3h 3.33uM EID0017
Types Number Response transcription factors
Up-regulation 60 EGR1; KDM5A; FOS; FOSB; TSC22D3; EGR3; SP140; ATF3; NR4A1; ZNF274; TBX2; PIAS1; NR4A2; RUNX3; CREB3L2; ARID4B; XBP1; BBX; IRF4; DDIT3; JUNB; TBL1X; HCFC2; MYBL1; ID2; TWIST1; GATA2; JUND; NCOA2; ZNF217; HDAC1; CHD7; TBPL1; FOXL2; TOB1; CTR9; EGR2; PITX1; SMAD5; KLF2; SSX1; SP140L; SOX10; ATF5; ZKSCAN1; SMARCD3; HOXC6; CITED1; NR2F1; TOX; ELF3; WT1; STAT4; TRPS1; SOX9; OSR2; NR2F2; EYA2; FOXF1; LEF1
Down-regulation 41 NFKBIA; MYC; HDGF; ETS1; TCF4; BCL11A; KLF7; ARNTL2; IRF6; PNRC1; ILF2; HLX; CTBP1; TFDP2; ETS2; RELB; AES; GTF3A; TLE2; ERG; RYBP; AEBP1; HMGA1; ZNF423; MYCL; NFKB1; ID1; MEOX2; SMAD1; BIRC2; INSM1; ZNF43; BACH2; SIX1; BTG1; HEY1; INSR; MNDA; ID3; DACH1; PBX3