Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12140 Torin-1 GSE70138 HME1 Human 3h 0.37uM EID0017
Types Number Response transcription factors
Up-regulation 76 TSC22D3; HDAC6; ARID4B; BRCA1; TBX2; CEBPD; TFCP2L1; NR4A1; ATF3; CALCOCO1; ARID5B; TSG101; ZBTB43; MAFF; FOSB; ZSCAN18; YBX1; TAF12; SKI; DDX17; NCOA1; ZNF589; KAT6B; EGR2; BBX; RNF141; TSC22D1; SMAD3; NR1H3; SOX4; ZNF331; NCOA3; KDM5D; BCLAF1; TBL1XR1; FOS; RBL2; TOX; KLF4; KLF11; PNRC1; ID4; ARNTL; KLF6; MBD2; TGIF1; BHLHE40; ZNF165; JUNB; TAF1D; MEF2A; XBP1; TXNIP; STAT1; ZNF532; MEIS1; DMTF1; TLE1; NR4A2; FOXF1; NR2F1; FOXC1; FOSL2; BHLHE41; NR1H2; WT1; BIRC2; NKX2-1; LPIN2; NFIL3; HMGB3; ETS2; PEG3; KLF9; NKX3-1; BASP1
Down-regulation 61 TCEA2; SLC2A4RG; SMAD1; ZNF232; TAF4; PCGF2; MED6; E2F6; CCNC; WWP1; HHEX; PPRC1; CEBPZ; E2F8; ZNF652; TERF1; NR2F6; HOXB7; SOX11; ZNF512B; TCF7; CBFB; NCOR2; PRPF6; MTA1; BACH2; SCAND1; HIRA; PRRX1; ZNF107; HTATIP2; TWIST1; SHOX2; RNF6; GTF3A; REPIN1; CERS6; IRF4; IRF8; RUNX3; HOXB2; MYT1L; ETV5; KAT2B; BNC2; HOXC6; VDR; ARID1A; EMX2; ZHX2; GATA6; LEF1; POU2AF1; ZNF423; HOXB6; MEIS2; TRIB3; PBX1; HOXA10; THAP11; ARNT2