Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12092 Azd-5438 GSE70138 HME1 Human 3h 0.37uM EID0017
Types Number Response transcription factors
Up-regulation 30 FOSL1; MYC; EGR1; BHLHE40; OVOL2; WT1; EGR3; PEG3; FLNA; CD3D; IRF7; ZBED2; ESR1; KLF2; ID4; MECOM; SUB1; TCF21; ZFPM2; BIRC2; TGFB1; KLF10; ZNF91; ETS2; ATF3; RBPMS; SOX9; MEIS2; EMX2; THAP11
Down-regulation 55 ADRB2; CCNA2; ADNP; TSC22D3; ARID4B; PIAS1; HMBOX1; PREB; MED23; HOXA5; DNMT3B; TP63; HBP1; CENPF; EED; FOXM1; E2F6; BASP1; BAZ1A; ZMYND8; TLE4; SOX10; TGIF1; TBL1XR1; NFE2; RREB1; TRIM32; NUP62; HTATIP2; BAZ2B; CHD9; ZNF721; RNF6; APEX1; BACH1; ZNF160; TFCP2; CEBPD; KLF4; FOXF2; IRF6; ZMYM2; HOXB7; ZBTB16; ABL1; SERTAD2; ARID1A; PURA; TRIM22; FOSL2; TBX3; ZFP36L2; TCF4; KDM5D; SUV39H1