Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12072 Bms-387032 GSE70138 HME1 Human 3h 3.33uM EID0017
Types Number Response transcription factors
Up-regulation 45 MED12; DNAJC1; TBX2; IRF5; KDM5A; HDAC6; CREB3L2; PLAGL1; FOXF1; RBBP4; BHLHE40; AEBP1; ZNF226; IRF6; NR2F1; FLNA; CHD4; DACH1; MYCL; SMARCB1; NR2F2; ESRRG; STAT3; PRRX1; HLTF; SP110; TCF21; NANOG; AES; CEBPZ; ZFHX3; NR4A1; TGFB1; VPS72; EYA1; MEIS1; CREB1; TCF4; EMX2; ISL1; ZNF91; HOXC6; PBX3; ASCL1; ESR1
Down-regulation 130 MYC; NFKBIA; FOSL1; NRIP1; ADRB2; JUN; FHL2; HMGA2; CEBPB; ZNF394; TOPORS; PLAGL2; TSC22D3; BTG1; NFIL3; NRBF2; ZFP36L2; HOXA1; FOXO1; PPRC1; ABT1; ZFX; ETS1; RELA; HOXA5; ATF4; MAFF; SERTAD2; BCL10; ZNF184; SNIP1; MYBL1; ZNF7; MED17; ZBTB11; CRY1; ZNF281; THAP1; POLR3F; AGO2; E2F3; KLF10; CEBPD; ABL1; RLF; ZNF292; ZNF84; SMAD3; ZBED4; JUNB; ARID4B; CHD7; TAF4; VEZF1; ZNF529; MDM2; TSC22D2; CEBPG; BACH1; SMAD7; ZNF189; MNT; SNAI2; ZNF93; ZNF468; CHD1; HIC2; HIPK1; KLF6; IRF1; TRIM32; ZNF623; KAT7; KLF4; AHR; BCOR; HIVEP1; PHF20; CITED2; NFKB1; JUND; CREB5; XBP1; FOSB; BACH2; ZMIZ1; FOXJ3; DDIT3; TAF1D; ZBTB1; ANKRD1; POU4F1; ELK3; TFAM; ARID5B; RREB1; HES1; TGIF1; ZEB2; ZEB1; ZFP36L1; HMGA1; TOX; BIRC2; E2F5; BCL11B; BAZ1A; KLF11; CD3D; ELF1; SATB2; ID1; DLX2; EGR3; BCL6; SOX11; TXNIP; ETS2; STAT4; ATF3; SATB1; RELB; CREM; LPIN2; IFI16; SUV39H1; TBX3; ZBTB16; MAFB; BASP1