Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12070 Canertinib GSE70138 HME1 Human 3h 0.04uM EID0017
Types Number Response transcription factors
Up-regulation 17 TSC22D3; ID2; TRIM16; HDAC1; LITAF; HOXA5; BCL3; ID1; HOXC6; TLE1; TWIST1; PSIP1; NR2F2; PIR; TOB1; THAP11; PEG3
Down-regulation 18 MYC; JUN; NPAS2; EGR3; NKX2-2; NKX2-1; EGR2; NR0B1; HOXD1; NR4A2; SATB2; BHLHE41; ZNF91; ZNF589; CREB1; KDM5D; ARNT2; ESR1