Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12069 Canertinib GSE70138 HME1 Human 3h 0.12uM EID0017
Types Number Response transcription factors
Up-regulation 35 PAX8; TSC22D3; TRIP4; CBX6; SALL1; NR2F2; NFATC3; BRD8; TRIM16; NFIB; FOXE1; TRIM29; COPS2; CRYM; MAGED1; NFIL3; EYA2; ID2; HMGB2; KAT6B; ZIC1; HOXB6; ZNF32; HOXB7; HOXC10; FOXC1; NR2F1; OSR2; PSIP1; PIR; MAF; HOXC6; EMX2; MAFB; PEG3
Down-regulation 40 MYC; FOSL1; JUN; TGFB1; REL; NR4A2; NLK; PITX1; SMAD4; PBX2; NR4A3; BCL10; MYB; E2F5; NR2F6; CHD1; FOXA1; KLF2; FOXF2; NR4A1; TGFB1I1; ETS2; INSM1; SMAD7; SATB2; RUNX1; GATA6; FOXF1; TSC22D2; TWIST1; LIN28A; CREB1; CREM; TOX3; MEIS2; SOX11; EGR3; EGR2; KLF10; KDM5D