Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12067 Canertinib GSE70138 HME1 Human 3h 1.11uM EID0017
Types Number Response transcription factors
Up-regulation 48 TSC22D3; MEF2C; FUBP1; NR2F2; XBP1; SOX3; DDIT3; PMS1; HMGB2; MECP2; NFIL3; PEG3; ZFPM2; SREBF1; SMAD5; JAK2; SMARCD3; HOXD3; TRPS1; STAT1; RNF141; CBX7; KLF2; NKX2-2; ERBB4; KAT6B; CREB3L2; RAD21; GATA6; TXNIP; CUX2; TLE1; ZMYND8; PBX1; EMX2; ZBTB20; JUP; NR4A2; TWIST1; CITED2; NR1D2; MYBL1; TRIB3; WT1; HHEX; MEIS1; NR2F1; MAFB
Down-regulation 23 MYC; HMGA2; FOSL1; ZNF146; JUN; ZNF574; SMAD7; NRIP1; ZNF281; DNMT3B; PDLIM1; TERF1; JUNB; BAZ1A; CRYM; NKX2-1; FOSB; SATB2; BHLHE40; HEY1; MSX1; MYB; DACH1