Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12065 Canertinib GSE70138 HME1 Human 3h 10uM EID0017
Types Number Response transcription factors
Up-regulation 20 TSC22D3; XBP1; SATB1; ATF4; NFE2L1; TADA3; NCOA1; AFF1; PIR; DDIT3; RXRA; SMARCA2; TWIST1; MED1; NFIL3; CREB1; TBL1X; TOB1; THAP11; BASP1
Down-regulation 38 MYC; FOSL1; HMGA2; JUN; ETS1; ADRB2; REL; KLF6; NRIP1; SMAD7; MAFF; ELK3; EGR3; CREB5; CBFB; RBBP8; HOXD1; AHR; NKX2-1; RCOR1; SNAI2; BACH1; PITX1; CEBPD; ETS2; NAB1; BIRC2; NR0B1; ZMIZ1; OSR2; HHEX; ZFP36L1; SOX9; EGR2; IFI16; MSX1; HOXB6; ESR1