Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12061 Afatinib GSE70138 HME1 Human 3h 1.11uM EID0017
Types Number Response transcription factors
Up-regulation 41 GATA2; TSC22D3; KDM5D; TRIM29; TLE4; RXRA; KAT2B; BRD8; ZEB2; OSR2; ZFPM2; TRIM16; SMAD6; CBX7; SMAD1; TRIP6; MAFB; AES; TRIM22; TLE1; MNDA; FOXJ3; NFIL3; PSIP1; ID1; NR2F2; EYA1; LPIN2; BIRC2; ERBB4; DACH1; FOXF1; WT1; MAF; ID4; MEIS1; TXNIP; THAP11; EMX2; TRIB3; BASP1
Down-regulation 30 MYC; FOSL1; ETS1; HMGA2; KLF6; KDM5C; CBFB; NFYA; FOXA2; HMBOX1; SMARCA1; TSC22D2; KLF7; NKX2-1; WWTR1; ABL1; TOX3; MAFF; ZNF165; BAZ1A; CREM; JUNB; FOSB; LITAF; INSM1; NR4A2; EGR2; EGR3; GATA6; SOX9