Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12051 Cgp-60474 GSE70138 HME1 Human 3h 0.12uM EID0017
Types Number Response transcription factors
Up-regulation 61 KDM5A; MAGED1; RFX5; CIITA; EGR1; GTF3A; HDAC6; ETV1; ZNF83; TAF12; CRYM; SIM1; AEBP1; ZNF248; STAT3; EMX2; HMGN3; RBBP8; SOX5; ZIC3; PRRX1; ZNF573; TAF10; PSMC3; SIX3; PBRM1; HDAC1; TTF2; BCL11A; RNF141; ARNTL2; RBBP4; SATB1; HEY2; AFF1; CBFA2T3; E2F2; CREB3L2; SMARCA1; HOXC6; ZSCAN18; SPDEF; SALL2; NR2F2; SCAND1; LEF1; TWIST1; MNDA; NFAT5; TFAP2C; ISL1; PEG3; MAF; ZNF91; ERBB4; TCF4; TXNIP; ZFPM2; HOXB2; FOXG1; ESR1
Down-regulation 133 MYC; FOSL1; NFKBIA; NRIP1; FHL2; JUN; ZNF394; PLAGL2; ADRB2; SMAD7; MED17; TSC22D3; ZFP36L2; MAFF; RNF4; ARID5A; CBX4; ETS1; RELA; ERF; KLF6; ADNP; JUNB; CEBPB; ZNF281; ARID4B; NR4A3; KLF10; RLF; PCGF1; FOXK2; ZBTB1; ZNF263; TSC22D2; NFIL3; DR1; ATF3; ZNF574; RBM39; DDIT3; PPRC1; BTG1; ADNP2; BCL10; ABL1; MAFG; TGIF1; IRF1; ZNF324; SRF; ZBTB11; SMAD3; XBP1; REL; ZNF282; NR1I2; SERTAD2; BHLHE40; VEZF1; NFYA; JUND; ZBED4; NFKB1; CHD7; KLF7; TAF7; KLF13; TFAP2A; CEBPG; RBM14; EED; KDM2A; RNF138; NRBF2; PCGF3; ZMIZ1; TBX3; HOXA5; ZNF12; SIRT7; HIC2; ING2; CCNE1; FOXF2; FOSB; FOXO1; BACH1; RYBP; RELB; ZBTB43; CRY1; BCL3; KLF11; HES1; FOSL2; NR4A2; GATA6; RNF6; AHR; SATB2; ARID5B; ELK3; KLF5; IRF9; RUNX3; ELF4; CEBPD; CHD1; NR4A1; SOX9; SNAI2; MYBL1; ETS2; WWTR1; IFI16; BASP1; ZBTB38; KAT6B; BRD2; EGR2; CITED1; NR2F6; SUB1; RORA; DLX2; BIRC2; TOB1; TOX3; ZEB1; NKX3-1; CREM; SUV39H1; TRIB3