Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12038 Pf-562271 GSE70138 HME1 Human 3h 0.37uM EID0017
Types Number Response transcription factors
Up-regulation 62 VGLL4; PSMC3; TSC22D3; RBFOX2; CLOCK; DAXX; MYBL1; RNF138; EGR3; FOXO1; NR3C2; CREB3L2; KLF2; THAP4; MSX1; SMARCC2; KAT2B; SMARCE1; ATF5; SIAH2; CNBP; FOXG1; WNT4; NR4A1; CRYM; CBX7; BCL6; ESR1; IRF8; KLF4; POU2AF1; TXNIP; IRF9; ZFP36L1; ZBTB20; MECOM; TAL1; MAFB; EYA1; NFIL3; IRX5; ID1; FOS; BRD4; SOX17; FOSB; SMAD1; ETS2; ATF3; HSBP1; NR4A2; DLX5; LPIN2; EGR2; BTG1; KLF10; MEOX2; TSC22D1; ZFPM2; LEF1; CREB1; ARNT2
Down-regulation 39 CCNA2; ETS1; LMCD1; INSM1; BATF; PURA; BHLHE41; ZNF146; PTRF; RUNX1; NR2F1; TEAD1; PREB; DACH1; TOX3; NUP62; BRD8; TRIM29; RUNX3; WWC1; ZMIZ1; JUN; ZNF652; PBX1; BMI1; RBPMS; ZKSCAN1; CREB3L1; KDM5D; AHR; CRY1; MYB; ZEB2; MYCN; PEG3; RELB; EHF; BASP1; MEIS1