Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11992	Fostamatinib	GSE70138	HME1	Human	3h	0.37uM	EID0017

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	MTF2; NKX2-1; ID2; RFXAP; TAF12; ORC2; EGR1; ZBTB44; CREB3L2; TSC22D3; ZNF443; RFX7; ZNF551; PURA; TOX4; ZNF165; NCOA1; ZSCAN31; ELF5; EN1; SUPT5H; SPIB; NLK; SOHLH2; HDAC6; ZSCAN18; SAP18; SKI; ZNF302; HMGB3; ZNF148; ZNF136; PPARGC1A; CEBPD; ZNF329; RSF1; RBL2; MDM2; TAF1D; GABPA; CBX6; EMX2; NR2E1; ZNF84; CREBZF; ZNF692; CUX1; SMARCA2; MED7; ZNF124; ARID4A; ZMIZ2; FOXG1; BRIP1; TFCP2L1; NPAS2; SMARCA1; SMAD6; HMGN3; L3MBTL1; PIAS2; PLAG1; TFDP2; ZNF44; RBM14; ZNF248; HMBOX1; CREB5; RBBP4; FOXE1; MAGED1; BTG1; MBD2; ZNF217; ZNF93; IRX5; IRF4; ZNF532; TXNIP; ZNF22; ETS2; ID4; ZBTB18; SSX1; RBPJ; HEY2; TLE2; HMGB1; RUNX3; FOXC1; ZNF512B; HSF2; ELF3; ZIC1; ZSCAN16; PIAS3; CBX5; RYBP; TBL1XR1; EGR3; ZNF350; SOX10; TBX3; ZNF107; TRIM29; GRHL2; PAX5; KLF2; TRIM22; NFAT5; ZNF226; NFIL3; NR1H3; KLF9; EYA2; MITF; NR1D2; ASCL1; ZBTB38; BHLHE40; HES1; PIR; ID1; WT1; RBPMS
Down-regulation	92	TCERG1; CREG1; DNAJC2; ZNF408; TFAP2A; ZMIZ1; NR0B2; MED17; ZNF394; AEBP1; HIPK1; TOB1; NR2F6; SOX11; PRDM4; NFE2L1; ACTL6A; ZBTB11; TULP3; VEZF1; PCGF3; RREB1; RBM39; ZMYND8; SMARCA4; PBX1; SCAND1; EWSR1; ZEB1; ZBTB17; NFIC; CHD4; CENPB; PITX1; CTBP1; SIAH2; HOXC4; JUP; GATA3; CBFA2T2; CBX4; RNF138; CTR9; PSMC3; HAND1; NR4A3; NFATC4; TERF1; SRCAP; ZNF232; TCF21; CEBPZ; KAT7; PHF20; RRN3; SFPQ; KLF10; CCDC59; TRIM16; TEAD4; BIRC2; HOXB2; BAZ1A; NR0B1; CERS6; SERTAD2; IRF7; MYB; BCL11B; FLNA; TGFB1; TRIB3; RXRA; STAT1; DDIT3; SUB1; TGFB1I1; HOXB6; GATA6; ZHX2; CRYM; HHEX; SPEN; SOX9; MEIS2; CREB1; MNDA; BRD4; MXI1; PBX3; ERBB4; KDM5D