Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11984 Gsk-1059615 GSE70138 HME1 Human 3h 3.33uM EID0017
Types Number Response transcription factors
Up-regulation 51 TSC22D3; GATA3; NFKBIA; HBP1; SOX4; ELF5; SETDB1; EZH1; RBFOX2; TRPS1; TP63; NR3C1; PRDM2; NCOA3; CITED2; CEBPD; ERBB4; TOB1; CDK8; SP140L; ZNF217; ATF3; MAGED1; BTG1; PBX1; NPAS2; MEF2A; TOX; ATF4; FOS; ZNF331; MECOM; RXRA; NFIL3; ZBTB16; ZHX2; MXI1; HDAC9; ST18; NR4A2; JUP; MEOX2; TRIB3; RORA; MEIS2; KLF9; TXNIP; POU2AF1; ARNT2; MAFB; ESR1
Down-regulation 35 FOSL1; HMGA2; GTF2A2; TBP; FHL2; CBFB; ETS1; HNRNPD; PPRC1; AFF1; SFPQ; SMAD2; PITX1; HOXB6; KLF10; JUN; RUNX1; CRY1; MAFF; BAZ1A; SAP30; SCAND1; HMGB2; EDF1; HOXC6; GRHL2; HSBP1; ELK3; MYCN; EGR3; CTNNB1; ETS2; ASCL1; NKX3-1; LEF1