Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11963	Alvocidib	GSE70138	HME1	Human	3h	0.12uM	EID0017

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	RFX5; SND1; ZNF224; CBX6; GLI2; TCF25; STAT2; SMARCA4; ETV1; LMCD1; ZMIZ2; WNT4; HMGN3; ARL2BP; AEBP1; FOXL2; IKZF1; PAX5; NR0B1; SMARCA1; SP110; TLE2; IRF8; CARHSP1; NKX2-2; ZFPM2; PAWR; TRIP6; PITX1; SALL2; PBX1; HLTF; CREB3L2; SPDEF; STAT6; RUNX1; CRYM; CREB1; TCF21; TCF4; PSIP1; FOXE1; ZHX2; TRIM22; JUP; HOXC6; MNDA; WT1; NR2F2; SPEN; EMX2; POU2AF1
Down-regulation	135	MYC; FOSL1; NFKBIA; ADRB2; NRIP1; FHL2; ZNF274; ETS1; ADNP; KLF6; JUN; JUNB; TSC22D2; ZFP36L2; MTF2; RLF; CHD1; ERF; PLAGL2; CEBPG; ARID4B; CEBPB; TLE1; GMEB2; JUND; NFIL3; SOX4; ZBED4; RBM39; TSC22D3; MED17; DR1; TAF4; FOSL2; ZNF84; NFYA; TGIF1; NUP62; MAFG; ZNF217; PIAS1; ZNF473; HOXA5; REST; SMAD7; VEZF1; ATF3; SERTAD2; BCL10; PPRC1; BACH1; MED6; KLF4; JARID2; FOSB; ZNF281; FOXD1; ZNF432; YWHAB; MAFF; KLF5; FOXK2; ARID5B; CRY1; ABL1; BRD2; TBX3; DDIT3; NR4A3; ETS2; TOPORS; ZBED1; TAF7; HMGXB4; ZNF654; NCOA1; CTCF; ZMYND8; RNF4; ZNF443; UBE2B; RELB; IKZF5; E2F3; KLF10; AHR; XBP1; ZNF140; BCL3; BIRC2; DNMT3B; BTG1; FOXF2; ZNF331; HLX; EGR3; HIC2; ZNF266; TOX3; BHLHE40; NRBF2; CAMTA1; HSF2; TOB1; HES1; CHD7; ZNF131; SCAND1; MED21; CEBPD; SNAI2; KLF11; NR4A2; KLF7; NR2F6; BCOR; PHIP; DLX2; TRPS1; TSC22D1; PLAGL1; FOXG1; ELF3; ZMIZ1; CITED2; ZBTB18; RORA; ZIC1; DAXX; SOX9; KLF9; ELK3; SUV39H1; MYBL1; KDM5D