Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11961 Alvocidib GSE70138 HME1 Human 3h 1.11uM EID0017
Types Number Response transcription factors
Up-regulation 70 GATA2; AEBP1; RFX5; KDM5A; RBFOX2; SUPT3H; ZNF224; KMT2D; JUP; MYCBP; MZF1; HMGN3; TAF1; ZNF467; EHMT2; ATN1; NFATC4; EZH1; ZNF264; CREB3L2; DBP; MECP2; ZSCAN18; TP53; TRIM16; SALL2; IRF4; MEIS2; PHOX2B; CALR; ZNF423; HDAC9; CSDE1; TGFB1I1; NANOG; MAZ; MYCL; TCEA1; KAT2B; ZNF652; TLE2; NFE2L3; EYA1; AES; BNC2; ZFPM2; ZFHX3; PSIP1; BHLHE40; TCF21; ISL1; IRF8; FOXN3; ST18; TRIM29; PBX1; TCF4; HLTF; IRF6; MECOM; POU2AF1; SATB1; FOXF1; TWIST1; ZNF91; MEIS1; KDM5D; PIR; PBX3; PDLIM1
Down-regulation 122 MYC; NFKBIA; FOSL1; KLF6; CEBPB; JUN; FHL2; NRIP1; ZFP36L2; GMNN; NRBF2; ARID4B; ZNF189; MED17; ZNF557; RNF138; NFIL3; MTF2; JUNB; ETS1; BTG1; VEZF1; ZBTB1; OLIG2; E2F3; PPRC1; BAZ1A; EGR3; CDK7; ZNF281; ZNF394; RREB1; ERF; TSC22D3; NUP62; TTF1; ZNF443; TRIM27; TGIF1; AGO2; RNF4; ZBTB11; TAF1D; SNAI2; FOSL2; TAF9; BRPF1; MED6; ZNF7; ADNP; KLF10; UBE2B; SERTAD2; ATF7IP; SIM2; PATZ1; EGR4; ZBED1; MAFG; ZNF410; PURA; ZNF529; TSC22D2; TBX3; TRIM32; FOXD1; IRX4; ATF3; MYBL1; NCOA4; ZNF146; ZBTB16; CHD1; REST; EED; LMCD1; BCL10; NR4A3; ZBTB43; AHR; ARID5B; NR3C1; BRD2; FOXJ3; KLF2; E2F8; ZMIZ1; RNF6; HES1; SMAD3; CEBPD; TSC22D1; KLF4; ELF1; GABPB1; CBFB; SIAH2; ZNF12; SOX9; RYBP; STAT1; NPAS2; MAFF; FOXO1; EGR2; BASP1; HOXA5; TERF2; ETS2; GATA6; ZNF107; ZNF22; IRX5; CITED1; DLX2; CREM; TOB1; ZEB1; TFEC; FOXG1; SUV39H1; HOXC6