Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11959	Alvocidib	GSE70138	HME1	Human	3h	10uM	EID0017

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	AEBP1; HSF4; TBX19; SIX6; ZNF688; TBX2; DBP; ZNF224; LZTR1; SIX3; CALCOCO1; MEF2C; CREBL2; HOXA4; ZNF771; GFI1B; PHOX2A; POU3F2; SUPT4H1; MZF1; FOXJ1; HDAC5; BCL11A; SOX2; NANOG; OVOL2; GATA2; CBX7; WT1; ZNF593; TCF21; PEX2; TP53; ZNF226; EYA1; HAND1; E2F2; HLF; NR1H4; CD3D; ZMYM2; PIR; CREB3L2; SMAD6; KAT2B; AR; ZNF532; SPDEF; MEIS2; FOS; IRF4; TWIST1; JUP; PBX3; ID4; FOXF1; SPEN; MNDA; POU2AF1; ESR1
Down-regulation	131	MYC; NFKBIA; FOSL1; NRIP1; HMGA2; FHL2; VGLL4; ADRB2; JUN; ZFP36L2; ADNP; USP22; ETS1; TBP; SOX4; NFIL3; CEBPB; TGIF1; CCNA2; CRK; TSC22D3; TSC22D2; JUND; KAT6A; MTF2; FOXO1; NRBF2; ZBED1; TRIM32; FOXJ3; PLAGL2; ZNF281; RNF111; NUP62; SF1; RELA; ZNF189; VEZF1; SMAD7; CDK7; ABL1; BHLHE40; ARID4B; SERTAD2; DDX17; BTG1; PPRC1; SETD2; MED23; JUNB; DNAJC2; YBX1; CEBPD; ZNF410; KLF4; KLF6; TXNIP; BACH1; CRY1; ELK3; HNRNPD; BRPF1; TAF4; PATZ1; PHF2; TERF2; EED; AHR; REST; ZFP36L1; TCF12; MED17; BCOR; RCOR1; MAML1; ZEB1; CBFB; NCOA1; ZEB2; ZNF217; HIVEP1; FOSL2; ZMIZ1; HSF2; CCNE1; IFI16; RBPJ; SMARCA2; BIRC2; RREB1; NFKB1; BAZ2B; ZBTB43; FOXO3; ID1; CHD7; YWHAB; ELF1; TCF7L1; HES1; MAF; KAT6B; EGR2; NR3C1; ELF5; BAZ1A; ELF4; KLF10; ATF3; ATF4; FOXD1; STAT3; ZIC1; TLE4; KLF2; TSC22D1; MYBL1; TOB1; SOX9; MSX1; ETS2; ZBTB38; NR2F6; TBX3; NR1D2; SOX11; RELB; ZBTB16; BASP1; KLF9; SUV39H1