Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11946 Withaferin-a GSE70138 HME1 Human 3h 0.04uM EID0016
Types Number Response transcription factors
Up-regulation 103 KDM5B; GATA3; HES1; TBX3; NKX2-1; NR2C1; ZNF329; BAZ2A; ZNF587; GATA2; IRX5; HOXA7; CARF; TLE4; HSBP1; BCL6; BAZ2B; BRDT; ZNF551; ERG; TFAP2B; PSMC3IP; ANKRD1; POU2AF1; ZBTB25; GFI1; MTF2; BCOR; FLI1; ZNF236; DMTF1; LYL1; HOXA5; DDX17; E2F2; RCOR3; CERS6; RCOR1; SSBP2; TFDP2; ARNTL2; RFX5; ASCL2; NLK; SIX3; PBX3; BHLHE41; SIX1; FOXA1; PIAS3; EGR2; RARA; HOXD3; ZNF22; BNC1; MBD4; ASCL1; DACH1; CTBP1; ZNF711; PITX2; REST; ZBED2; ZNF516; NRBF2; RERE; IRF2; ID3; HAND1; KLF13; DNMT3B; TFAP2C; MNAT1; TAL1; ID4; SMARCC2; INSM1; ISL1; DLX2; MYB; RBPMS; ID1; NPAS2; CITED1; ZNF83; LIN28A; PHOX2B; PNRC1; CRYM; ZBTB18; IRF4; MEOX2; MAFB; HMGN3; ZNF423; ZBTB20; LMCD1; SOX11; HOXB6; TRIM22; TFEC; LEF1; HOXC6
Down-regulation 37 XRCC6; BATF; KLF9; LITAF; ELF4; TCF25; SPIB; SMARCB1; JUNB; PRPF6; RUNX3; ZNF91; CREB3L1; EMX2; MITF; PURA; MAFF; PIR; SHOX2; ZBED1; ZIC1; HDAC9; BATF3; YWHAB; NAB1; BCL3; LOXL2; SATB2; IRF8; MEIS1; KDM5D; RXRA; KLF6; MAF; BCL11A; EYA2; IKZF1