Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11945 Withaferin-a GSE70138 HME1 Human 3h 0.12uM EID0016
Types Number Response transcription factors
Up-regulation 52 SPDEF; TCFL5; POU5F1B; HHEX; ABL1; TBL1X; SIAH2; AR; KLF4; PHF20; CBFA2T3; SSBP3; CREM; GATA3; TCF7; POU2AF1; CERS4; ZHX2; ATF5; ZNF107; RUNX1; ZNF721; SOX10; NANOG; NFATC1; PBX3; HOXD1; DLX2; ESR1; GRHL2; ZNF160; TOB1; HOXC6; TFAP2C; LIN28A; BCL11A; GATA2; IRX5; PAX5; TLE4; PAWR; FOSB; INSR; TBX3; ZFPM2; ARNT2; PBX1; MAFB; TRIM22; MNDA; PEG3; HMG20B
Down-regulation 35 TLE1; EED; NUP62; RELB; DEK; TGFB1I1; SP2; VEZF1; NFIL3; BHLHE40; TAF9B; ETS2; NFE2L1; HOXA5; MECOM; SMAD7; BRD8; SIX2; ZNF22; CTR9; KLF9; ASCL1; HLTF; NR1D2; ID4; TSC22D3; SIX1; TGFB1; VPS72; MITF; FLNA; KDM5D; TWIST1; HMGB3; TRIM29