Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11942 Withaferin-a GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 44 FOS; EGR1; FOSB; JUN; NR4A2; NR4A1; DDIT3; FOXO3; JUNB; ZNF394; ARID5B; TCF25; ATF3; ID3; GTF2F1; MEIS2; POU2AF1; FOXD1; ZNF331; TGFB1I1; ID1; XBP1; RBFOX2; TWIST1; BRD2; STAT1; LEF1; TSC22D3; EGR3; ZBED2; RUNX1; JUP; TFAP2C; EYA2; RBPJ; SATB1; ZFP36L1; EGR2; PIR; PBX1; TRIM29; MECOM; NR2F6; HMG20B
Down-regulation 42 RELB; SUZ12; MYC; C1D; SOX4; GABPB1; ETS2; NFKB1; ATF1; CREB5; VEZF1; AHR; HIVEP1; MYCN; MTDH; TFEC; RAN; HLF; BCL3; ZNF22; CBX3; CRYM; CTNNB1; RAD21; RBPMS; SPEN; NKX3-1; NRIP1; NFIB; HMGN3; SOX9; TOX3; ERG; BCL11A; PAX6; GATA6; NKX2-2; HOXB6; THAP11; CREB1; PEG3; IKZF1