Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11941 Withaferin-a GSE70138 HME1 Human 3h 10uM EID0016
Types Number Response transcription factors
Up-regulation 28 NR1H2; FOS; FOSB; EGR1; NR4A1; E2F2; KLF1; TRIM28; SALL2; ZNF692; NR4A2; TSC22D3; TULP3; TSC22D1; MITF; PSIP1; ZNF331; CITED2; TFAP2C; HOXB7; ATF3; ESR1; CARHSP1; ARNT2; TOB1; RBPMS; THAP11; BASP1
Down-regulation 36 RELB; GABPB1; IKBKAP; SNAI2; ATF1; HIPK3; IRF1; SMAD7; TRAK1; NFKB1; CHD7; SMAD6; NR1D2; BACH1; ZEB2; NR2F6; CREB5; ID4; SMAD3; NKX3-1; SERTAD2; BCL3; IRF9; MSX1; TRIM22; TRIM16; SPEN; SOX9; HHEX; ZNF423; SATB2; GATA6; IRF8; MNAT1; ZIC1; IKZF1