Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11940 Mitoxantrone GSE70138 HME1 Human 3h 0.04uM EID0016
Types Number Response transcription factors
Up-regulation 60 FOXF1; CERS6; VGLL4; TOPORS; FOXF2; RNF14; NR3C2; ETS2; ZNF189; KAT2B; KLF1; GATA6; PRMT2; EN2; SMAD6; CEBPZ; POU4F1; SIAH2; BCOR; BRIP1; WWP1; HIVEP1; IRX5; ZFPM2; CDK8; CREM; RB1; PAX6; MAF; SATB1; CTNNB1; SMAD7; NHLH2; FOXD1; NFE2; REL; TFEC; TCF7; PSIP1; CALR; SATB2; PCGF2; RBPMS; TSC22D1; ZNF721; KLF9; CREG1; LEF1; LITAF; ZIC1; ZHX2; MYBL1; BTG1; ID4; CD3D; ZNF331; TRIP6; HOXC6; PBX1; TXNIP
Down-regulation 52 TCERG1; KLF13; MEF2C; MYCN; MAZ; HEY2; CCNE1; NRBF2; E2F6; RBBP8; PLAG1; TCF25; ZNF532; IL16; CRY1; TRIM29; BRD4; HLX; MDM2; CEBPG; KLF4; ASCL1; TDRD3; BACH2; EGR2; FLNA; ZBED1; PBX3; FOXG1; NRIP1; PEG3; SIX1; RUNX1; KLF11; INSR; HTATIP2; CARHSP1; HHEX; ZSCAN18; TCF7L2; RBPJ; ELF3; MEIS1; HEY1; EMX2; HOXA10; HOXB6; MAFB; ZNF423; HOXB2; THAP11; IKZF1